SCHEMBL7056829

SCHEMBL7056829

CC(CC(=O)O[SiH3])c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 1/20 0.48
LTB4R2 Q9NPC1 1/20 0.48
HPGD P15428 3/20 0.48
ALDH1A1 P00352 3/20 0.48
FFAR1 O14842 1/20 0.47
CYP3A4 P08684 1/20 0.46
CYP2C19 P33261 1/20 0.46
RAB9A P51151 1/20 0.46
POLB P06746 2/20 0.45
BCHE P06276 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
TAAR1 Q96RJ0 2/20 0.44
TRPA1 O75762 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9909362 0.83 HPGD (0.56) LTB4RLTB4R2HPGDALDH1A1FFAR1
SCHEMBL1894982 0.83 HPGD (0.56) LTB4RLTB4R2HPGDALDH1A1FFAR1
SCHEMBL706628 0.82 ALDH1A1 (0.49) HPGDALDH1A1CYP2C19POLBNPSR1
SCHEMBL28115672 0.81 ALDH1A1 (0.51) LTB4RLTB4R2HPGDALDH1A1FFAR1
SCHEMBL28191982 0.81 LTB4R (0.48) LTB4RLTB4R2HPGDALDH1A1FFAR1
SCHEMBL11442263 0.81 TSHR (0.58) LTB4RLTB4R2HPGDALDH1A1FFAR1
SCHEMBL27476164 0.81 TAAR1 (0.48) LTB4RLTB4R2HPGDALDH1A1FFAR1
SCHEMBL27982253 0.81 BCHE (0.49) LTB4RLTB4R2HPGDALDH1A1FFAR1
SCHEMBL23027267 0.80 LTB4R (0.54) LTB4RLTB4R2HPGDALDH1A1FFAR1
SCHEMBL13572924 0.80 LTB4R (0.54) LTB4RLTB4R2HPGDALDH1A1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1006118-B1 Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond DOW CORNING ASIA LTD (JP) 2003-05-07 EP disclosed
US-6175031-B1 PLATINUM-CATALYZED HYDROSILYLATION BETWEEN SIH-SUBSTITUTED SILICON COMPOUNDS AND UNSATURATED GROUP-FUNCTIONAL ORGANIC OR ORGANOSILICON COMPOUNDS IN PRESENCE OF A (ACYLOXY)-FUNCTIONAL HYDROGENSILANE COMPOUND OR ACID AND HYDRO(ALKOXY)SILANE DOW CORNING ASIA, LTD. (JP) 2001-01-16 US disclosed
US-6111126-A Method for synthesizing organosilicon compounds that contain a functional group bonded to silicon across the Si-C bond DOW CORNING ASIA, LTD. (JP) 2000-08-29 US disclosed
EP-1006118-A2 Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond Dow Corning Asia, Ltd. (JP) 2000-06-07 EP disclosed