Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 5/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3047967 | 0.81 | MCL1 (0.41) | GABRG2GABRB3GABRA3GABRA1LMNA | |
| SCHEMBL5231392 | 0.77 | MYC (0.49) | GABRG2GABRB3GABRA3GABRA1BRD4 | |
| SCHEMBL31032995 | 0.76 | GABRA1 (0.47) | GABRG2GABRB3GABRA3GABRA1BRD4 | |
| SCHEMBL3045673 | 0.72 | RAB9A (0.51) | GABRG2GABRB3GABRA3GABRA1BRD4 | |
| SCHEMBL3055280 | 0.71 | SMN1; SMN2 (0.37) | LMNAALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL25148606 | 0.71 | GABRA1 (0.59) | GABRG2GABRB3GABRA3GABRA1BRD4 | |
| SCHEMBL28192083 | 0.69 | KDM4E (0.42) | GABRG2GABRB3GABRA3GABRA1BRD4 | |
| SCHEMBL4284402 | 0.69 | NR4A2 (0.44) | GABRG2GABRB3GABRA3GABRA1BRD4 | |
| SCHEMBL30365014 | 0.68 | GABRA1 (0.56) | GABRG2GABRB3GABRA3GABRA1BRD4 | |
| SCHEMBL2284288 | 0.67 | BRD4 (0.54) | GABRG2GABRB3GABRA3GABRA1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1982978-B1 | PYRIDONE DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2014-08-27 | — | — | EP | disclosed |
| US-8076487-B2 | Pyridone derivative and herbicide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-12-13 | — | — | US | disclosed |
| US-20100222592-A1 | Pyridone Derivative and Herbicide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-09-02 | — | — | US | disclosed |
| EP-1982978-A1 | PYRIDONE DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2008-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222592-A1 | Pyridone Derivative and Herbicide | PDXK, PNPO, CBR3 | GABRG2 4098/4885GABRB3 4105/4885GABRA3 4041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.