Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL546542 | 0.92 | KMT2A (0.38) | KMT2ATSHRSMN1; SMN2NPSR1EPHX1 | |
| SCHEMBL28784937 | 0.85 | SMN1; SMN2 (0.36) | TSHRSMN1; SMN2HTR2ALMNA | |
| SCHEMBL6651178 | 0.74 | KMT2A (0.40) | KMT2ATSHRSMN1; SMN2EPHX1THRB | |
| SCHEMBL1782470 | 0.74 | KMT2A (0.40) | KMT2ATSHRSMN1; SMN2EPHX1THRB | |
| SCHEMBL31499299 | 0.74 | KMT2A (0.40) | KMT2ATSHREPHX1THRBTAAR1 | |
| SCHEMBL5503227 | 0.71 | KMT2A (0.38) | KMT2ATSHRSMN1; SMN2NPSR1EPHX1 | |
| SCHEMBL24243366 | 0.69 | LMNA (0.36) | KMT2ATSHREPHX1THRBTAAR1 | |
| SCHEMBL24002249 | 0.68 | THRB (0.38) | KMT2AEPHX1THRBTAAR1LMNA | |
| SCHEMBL20610222 | 0.68 | ALDH1A1 (0.50) | KMT2ATSHRLMNAMEN1 | |
| SCHEMBL14584327 | 0.67 | SLC6A4 (0.39) | KMT2ATSHREPHX1THRBTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105683159-B | Intermediates and methods for the synthesis of calicheamicin derivatives | 辉瑞大药厂 | 2017-12-19 | — | — | CN | disclosed |