Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ACP3 | P15309 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL28192145 | 0.92 | KMT2A (0.33) | KMT2AEPHX1THRBTSHRSMN1; SMN2 | |
| SCHEMBL28784937 | 0.82 | SMN1; SMN2 (0.36) | TSHRSMN1; SMN2ALDH1A1HTR2AKCNH2 | |
| SCHEMBL1782470 | 0.81 | KMT2A (0.40) | KMT2AEPHX1THRBDPP4F2 | |
| SCHEMBL6651178 | 0.81 | KMT2A (0.40) | KMT2AEPHX1THRBDPP4F2 | |
| SCHEMBL31499299 | 0.81 | KMT2A (0.40) | KMT2AEPHX1THRBDPP4F2 | |
| SCHEMBL5503227 | 0.77 | KMT2A (0.38) | KMT2AEPHX1THRBDPP4F2 | |
| SCHEMBL24002249 | 0.74 | THRB (0.38) | KMT2AEPHX1THRBL3MBTL1ALDH1A1 | |
| SCHEMBL20610222 | 0.74 | ALDH1A1 (0.50) | KMT2ATSHRALDH1A1CYP2D6 | |
| SCHEMBL913100 | 0.71 | KMT2A (0.41) | KMT2ADPP4F2TSHRL3MBTL1 | |
| SCHEMBL24243366 | 0.71 | LMNA (0.36) | KMT2AEPHX1THRBTSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104530417-B | A kind of multiple functionalized H types polyethyleneglycol derivative and preparation method thereof | 厦门赛诺邦格生物科技股份有限公司 | 2017-09-08 | — | — | CN | claimed |
| CN-104530415-B | A kind of different functionalization Y types polyethyleneglycol derivative, preparation method and its bio-related substance | 厦门赛诺邦格生物科技股份有限公司 | 2017-09-01 | — | — | CN | claimed |
| CN-104530415-A | Hetero-functionalized Y-type polyethylene glycol derivative, preparation method and biologically related substance thereof | XIAMEN SINOPEG BIOTECH INC | 2015-04-22 | — | — | CN | claimed |
| CN-104530417-A | Multifunctional H-type polyethylene glycol derivative and preparation method thereof | XIAMEN SINOPEG BIOTECH INC | 2015-04-22 | — | — | CN | claimed |
| CN-104109235-A | Mono-functionalized polyethylene glycol with nitrogen atom branched center and its preparation method and biologically-relevant matter | XIAMEN SINOPEG BIOTECH CO LTD | 2014-10-22 | — | — | CN | claimed |
| EP-2465541-B1 | Improved processes for making hydrazides | WYETH LLC (US) | 2018-07-18 | — | — | EP | disclosed |
| CN-108047287-A | For synthesizing the intermediate of Calicheamicin derivative and method | 辉瑞大药厂 | 2018-05-18 | — | — | CN | disclosed |
| CN-104725628-B | A kind of single functionalization branched polyethylene glycol, preparation method and its bio-related substance containing degradable group | 厦门赛诺邦格生物科技股份有限公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-105683159-B | Intermediates and methods for the synthesis of calicheamicin derivatives | 辉瑞大药厂 | 2017-12-19 | — | — | CN | disclosed |
| CN-104530417-B | A kind of multiple functionalized H types polyethyleneglycol derivative and preparation method thereof | 厦门赛诺邦格生物科技股份有限公司 | 2017-09-08 | — | — | CN | disclosed |
| CN-104530415-B | A kind of different functionalization Y types polyethyleneglycol derivative, preparation method and its bio-related substance | 厦门赛诺邦格生物科技股份有限公司 | 2017-09-01 | — | — | CN | disclosed |
| CN-104530413-B | A kind of bio-related substance of multiple functionalized H types polyethyleneglycol derivative modification | 厦门赛诺邦格生物科技股份有限公司 | 2017-08-25 | — | — | CN | disclosed |
| US-20040096893-A1 | Functionalised silicon surfaces, and method for their production | BOUKHERROUB RABAH (CA) | 2004-05-20 | — | — | US | disclosed |
| US-6677163-B1 | SIMPLE AND DURABLE IMMOBILIZATION OF BIOMOLECULES | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2004-01-13 | — | — | US | disclosed |
| EP-0716604-A4 | THIOL-DERIVATIZED NUCLEOSIDES AND OLIGONUCLEOSIDES | ISIS PHARMACEUTICALS INC (US) | 2000-12-27 | — | — | EP | disclosed |
| WO-2000068257-A1 | C-LINKED NEOGLYCOPEPTIDES, THEIR COMBINATORIAL SYNTHESIS AND USE | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2000-11-16 | — | — | WO | disclosed |
| EP-0716604-A1 | THIOL-DERIVATIZED NUCLEOSIDES AND OLIGONUCLEOSIDES | ISIS PHARMACEUTICALS, INC. (US) | 1996-06-19 | — | — | EP | disclosed |
| WO-1996014873-A2 | COVALENTLY BOUND β-GLUCAN CONJUGATES IN TARGETED DELIVERY | SRI INTERNATIONAL (US) | 1996-05-23 | — | — | WO | disclosed |
| WO-1995006474-A1 | THIOL-DERIVATIZED NUCLEOSIDES AND OLIGONUCLEOSIDES | ISIS PHARMACEUTICALS, INC. (US) | 1995-03-09 | — | — | WO | disclosed |
| EP-0132101-A1 | 2-Heterocycloalkylthiopenem derivatives | PFIZER INC. (US) | 1985-01-23 | — | — | EP | disclosed |