Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2283410 | 0.87 | RXRA (0.53) | KDM4EHPGDHSD17B10MAPTGAA | |
| SCHEMBL23241569 | 0.86 | RXRA (0.49) | KDM4EHPGDHSD17B10MAPTGAA | |
| SCHEMBL20045090 | 0.86 | HPGD (0.47) | KDM4EHPGDHSD17B10MAPTGAA | |
| SCHEMBL11217379 | 0.84 | KLKB1 (0.35) | GAALMNASRD5A2MEN1KMT2A | |
| SCHEMBL15862189 | 0.83 | GAA (0.52) | KDM4EHPGDHSD17B10MAPTGAA | |
| SCHEMBL25564411 | 0.83 | F10 (0.35) | ALDH1A1RXRARXRBKLKB1 | |
| SCHEMBL20943235 | 0.81 | ALDH1A1 (0.54) | HPGDMAPTGAATSHRNFKB1 | |
| SCHEMBL969589 | 0.79 | HPGD (0.55) | KDM4EHPGDHSD17B10MAPTGAA | |
| SCHEMBL4833201 | 0.79 | KDM4E (0.47) | KDM4EHPGDHSD17B10MAPTGAA | |
| SCHEMBL4841378 | 0.79 | CA2 (0.61) | KDM4EHPGDHSD17B10MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107522634-A | Biaryl ureas carboxylic acid derivates or its salt and its production and use | 复旦大学 | 2017-12-29 | — | — | CN | disclosed |