Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4153728 | 0.84 | ACHE (0.52) | ACHEALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL1838733 | 0.83 | ALDH1A1 (0.49) | OPRM1ACHEALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11247639 | 0.81 | KDM4E (0.46) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL1832831 | 0.79 | MTNR1A (0.49) | ACHEALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL10099720 | 0.78 | MEN1 (0.62) | ACHEALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11855609 | 0.78 | MTNR1A (0.70) | ALDH1A1SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL13852906 | 0.76 | MEN1 (0.49) | ACHEALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL27526983 | 0.75 | TP53 (0.53) | ACHEALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL17361052 | 0.75 | LTB4R2 (0.47) | OPRM1ACHEALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9261769 | 0.74 | ALDH1A1 (0.66) | DRD2DRD4OPRM1DRD3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105541750-B | A kind of preparation method of Mirabegron analysis of control product | 湖南方盛制药股份有限公司 | 2018-01-05 | — | — | CN | disclosed |