Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9444077 | 0.91 | LMNA (0.69) | LMNAALDH1A1TSHRMAPK1CYP3A4 | |
| SCHEMBL7732291 | 0.91 | TSHR (0.74) | LMNAALDH1A1TSHRMAPK1CYP3A4 | |
| SCHEMBL7521612 | 0.86 | LMNA (0.72) | LMNAALDH1A1TSHRMAPK1CYP3A4 | |
| SCHEMBL18069229 | 0.85 | LMNA (0.74) | LMNAALDH1A1TSHRMAPK1CYP3A4 | |
| SCHEMBL9062509 | 0.84 | LMNA (0.69) | LMNAALDH1A1TSHRMAPK1CYP3A4 | |
| Octisalate SCHEMBL31160278 | 0.83 | LMNA (1.00) | LMNAALDH1A1TSHRMAPK1CYP3A4 | |
| Octisalate SCHEMBL29362543 | 0.83 | LMNA (1.00) | LMNAALDH1A1TSHRMAPK1CYP3A4 | |
| Octisalate SCHEMBL31160283 | 0.83 | LMNA (1.00) | LMNAALDH1A1TSHRMAPK1CYP3A4 | |
| Octisalate SCHEMBL1923015 | 0.83 | LMNA (1.00) | LMNAALDH1A1TSHRMAPK1CYP3A4 | |
| Octisalate SCHEMBL14764329 | 0.83 | LMNA (1.00) | LMNAALDH1A1TSHRMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170135933-A1 | PHOTOPROTECTIVE COMPOSITIONS COMPRISING PHOTOSENSITIVE 1,3,5-TRIAZINE COMPOUNDS, DIBENZOYLMETHANE COMPOUNDS AND SILICEOUS S-TRIAZINES SUBSTITUTED WITH TWO AMINOBENZOATE OR AMINOBENZAMIDE GROUPS | L'OREAL (FR) | 2017-05-18 | — | — | US | disclosed |
| US-9526924-B2 | Composition comprising a screening agent of the lipophilic 2-hydroxybenzophenone type and a silicon-compromising s-triazine substituted by at least two alkylaminobenzoate groups | L'OREAL (FR) | 2016-12-27 | — | — | US | disclosed |
| US-8999299-B2 | Photoprotective cosmetic compositions comprising silicon-containing s-triazine compounds substituted with two aminobenzoate or aminobenzamide groups and non-silicon-containing lipophilic triazine compound UV-screening agents | L'OREAL (FR) | 2015-04-07 | — | — | US | disclosed |
| US-8747816-B2 | UV-photoprotective compositions comprising diebenzoylmethane screening agents and silicon-containing s-triazine compounds substituted with two aminobenzoate or aminobenzamide groups | L'OREAL (FR) | 2014-06-10 | — | — | US | disclosed |
| CN-101184763-B | Photostabilization of dibenzoylmethane by silicon-containing s-triazines substituted with two aminobenzoate or aminobenzamide groups, photoprotective compositions, novel silicon-containing s-triazine compounds | OREAL | 2013-01-16 | — | — | CN | disclosed |
| US-20120201767-A1 | COMPOSITION COMPRISING A SCREENING AGENT OF THE LIPOPHILIC 2-HYDROXYBENZOPHENONE TYPE AND A SILICON-COMPRISING S-TRIAZINE SUBSTITUTED BY AT LEAST TWO ALKYLAMINOBENZOATE GROUPS | L'OREAL (FR) | 2012-08-09 | — | — | US | disclosed |
| CN-102548528-A | Composition containing at least one lipophilic 2-hydroxybenzophenone filter and a silicon s-triazine substituted by at least two alkylaminobenzoate groups | OREAL | 2012-07-04 | — | — | CN | disclosed |
| EP-1891079-B1 | PHOTOSTABILIZATION OF A DIBENZOYLMETHANE BY A SILICON- CONTAINING S-TRIAZINE SUBSTITUTED WITH TWO AMINOBENZOATE OR AMINOBENZAMIDE GROUPS; PHOTOPROTECTIVE COMPOSITIONS. NOVEL SILICON-CONTAINING S-TRIAZINE COMPOUNDS | OREAL (FR) | 2010-10-27 | — | — | EP | disclosed |
| US-20100003207-A1 | Photoprotective compositions comprising photosensitive 1,3,5-triazine compounds, dibenzoylmethane compounds and siliceous s-triazines substituted with two aminobenzoate or aminobenzamide groups | L'OREAL (FR) | 2010-01-07 | — | — | US | disclosed |
| US-20080145324-A1 | UV-photoprotective compositions comprising diebenzoylmethane screening agents and silicon-containing s-triazine compounds substituted with two aminobenzoate or aminobenzamide groups | L'OREAL (FR) | 2008-06-19 | — | — | US | disclosed |
| US-20080138303-A1 | Photoprotective cosmetic compositions comprising silicon-containing s-triazine compounds substituted with two aminobenzoate or aminobenzamide groups and non-silicon-containing lipophilic triazine compound UV-screening agents | L'OREAL (FR) | 2008-06-12 | — | — | US | disclosed |
| EP-1891079-A1 | PHOTOSTABILIZATION OF A DIBENZOYLMETHANE BY A SILICON- CONTAINING S-TRIAZINE SUBSTITUTED WITH TWO AMINOBENZOATE OR AMINOBENZAMIDE GROUPS; PHOTOPROTECTIVE COMPOSITIONS. NOVEL SILICON-CONTAINING S-TRIAZINE COMPOUNDS | L'Oréal (FR) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006128732-A1 | PHOTOSTABILIZATION OF A DIBENZOYLMETHANE BY A SILICON- CONTAINING S-TRIAZINE SUBSTITUTED WITH TWO AMINOBENZOATE OR AMINOBENZAMIDE GROUPS; PHOTOPROTECTIVE COMPOSITIONS. NOVEL SILICON-CONTAINING S-TRIAZINE COMPOUNDS | L'OREAL (FR) | 2006-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080145324-A1 | UV-photoprotective compositions comprising diebenzoylmethane screening agents and silicon-containing s-triazine compounds substituted with two aminobenzoate or aminobenzamide groups | TST, TYR, DDT | LMNA 2847/4885ALDH1A1 1477/4885TSHR 4029/4885 |
| US-20120201767-A1 | COMPOSITION COMPRISING A SCREENING AGENT OF THE LIPOPHILIC 2-HYDROXYBENZOPHENONE TYPE AND A SILICON-COMPRISING S-TRIAZINE SUBSTITUTED BY AT LEAST TWO ALKYLAMINOBENZOATE GROUPS | STS, TST, ARSA | LMNA 2221/4885ALDH1A1 370/4885TSHR 2096/4885 |
| US-20100003207-A1 | Photoprotective compositions comprising photosensitive 1,3,5-triazine compounds, dibenzoylmethane compounds and siliceous s-triazines substituted with two aminobenzoate or aminobenzamide groups | CUTA, TST, DSG1 | LMNA 2246/4885ALDH1A1 3175/4885TSHR 4196/4885 |
| US-20170135933-A1 | PHOTOPROTECTIVE COMPOSITIONS COMPRISING PHOTOSENSITIVE 1,3,5-TRIAZINE COMPOUNDS, DIBENZOYLMETHANE COMPOUNDS AND SILICEOUS S-TRIAZINES SUBSTITUTED WITH TWO AMINOBENZOATE OR AMINOBENZAMIDE GROUPS | CUTA, TST, DSG1 | LMNA 2246/4885ALDH1A1 3175/4885TSHR 4196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.