Fluorene

Fluorene

SCHEMBL28192829

Oc1cc2ccccc2c2ccccc12.c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM4 Q8TD43 1/20 0.68
NQO2 P16083 1/20 0.46
CYP3A4 P08684 2/20 0.42
CYP1A2 P05177 2/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 2/20 0.42
MAPT P10636 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HPGD P15428 2/20 0.42
LMNA P02545 1/20 0.42
HSD17B10 Q99714 3/20 0.41
TSHR P16473 2/20 0.41
MAPK1 P28482 2/20 0.41
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL508755 0.82 TRPM4 (1.00) TRPM4NQO2CYP1A2ALDH1A1MAPT
SCHEMBL29399180 0.82 TRPM4 (1.00) TRPM4NQO2CYP1A2ALDH1A1MAPT
Methane SCHEMBL28286720 0.80 TRPM4 (0.95) TRPM4NQO2CYP1A2ALDH1A1MAPT
Hydrochloric Acid SCHEMBL28248720 0.80 TRPM4 (0.95) TRPM4NQO2CYP1A2ALDH1A1MAPT
Phosphine SCHEMBL28051726 0.80 TRPM4 (0.95) TRPM4NQO2CYP1A2ALDH1A1MAPT
Benzo[B]Triphenylene SCHEMBL28290123 0.79 KDM4E (0.48) CYP3A4CYP1A2NPC1RAB9AALDH1A1
Phenanthrene SCHEMBL21219119 0.78 TSHR (0.57) CYP3A4CYP1A2NPC1RAB9AALDH1A1
Triphenylene SCHEMBL21360057 0.78 MAOA (0.59) CYP3A4CYP1A2NPC1RAB9AALDH1A1
Fluorene SCHEMBL870544 0.78 CYP1A2 (0.65) NQO2CYP3A4CYP1A2NPC1RAB9A
Fluorene SCHEMBL28113829 0.78 CYP1A2 (0.65) NQO2CYP3A4CYP1A2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106471035-B Electronic material composition epoxy resin, its solidfied material and electronic component DIC株式会社 2019-04-16 CN disclosed
CN-105829388-B Epoxy resin, its manufacture method, composition epoxy resin and its solidfied material DIC株式会社 2018-01-12 CN disclosed
CN-106471035-A Electronic material composition epoxy resin, its solidfied material and electronic component DIC株式会社 2017-03-01 CN disclosed
CN-105829388-A Epoxy resin, method for producing same, epoxy resin composition, and cured product thereof DIC株式会社 2016-08-03 CN disclosed