Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13545147 | 0.85 | PTGS1 (0.44) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL3470155 | 0.83 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL9816728 | 0.80 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28480844 | 0.77 | PTGS2 (0.44) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1397437 | 0.77 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1918364 | 0.75 | L3MBTL1 (0.46) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1254599 | 0.74 | CYP2D6 (0.49) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL12424205 | 0.74 | NPC1 (0.40) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL3265864 | 0.74 | NPC1 (0.40) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL23352536 | 0.73 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247593-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL PREPARATIONS | DICOTYLEDON AB (SE) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100247593-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL PREPARATIONS | PDE4B, ACHE, PDE5A | NPC1 3274/4885RAB9A 291/4885SMN1; SMN2 3067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.