Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.63 |
| ▸ | NOD1 | Q9Y239 | 7/20 | 0.60 |
| ▸ | NOD2 | Q9HC29 | 5/20 | 0.60 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | BID | P55957 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28195762 | 0.86 | ALOX5 (0.60) | ALOX5NOD1NOD2CCR2ALDH1A1 | |
| SCHEMBL16792454 | 0.82 | ALOX5 (0.58) | ALOX5NOD1NOD2CCR2ALDH1A1 | |
| SCHEMBL28074030 | 0.82 | ALOX5 (0.58) | ALOX5NOD1NOD2CCR2ALDH1A1 | |
| SCHEMBL16792457 | 0.82 | ALOX5 (0.58) | ALOX5NOD1NOD2CCR2ALDH1A1 | |
| SCHEMBL16792452 | 0.82 | ALOX5 (0.58) | ALOX5NOD1NOD2CCR2ALDH1A1 | |
| SCHEMBL16792477 | 0.81 | NOD1 (0.65) | ALOX5NOD1NOD2CCR2ALDH1A1 | |
| SCHEMBL16794402 | 0.80 | NOD1 (0.71) | ALOX5NOD1NOD2CCR2ALDH1A1 | |
| SCHEMBL18331942 | 0.80 | ALOX5 (0.42) | ALOX5NOD1NOD2ALDH1A1LMNA | |
| SCHEMBL18332209 | 0.79 | NOD1 (0.41) | ALOX5NOD1NOD2ALDH1A1LMNA | |
| SCHEMBL9622915 | 0.79 | NOD1 (0.62) | ALOX5NOD1NOD2CCR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105722834-B | Tyrosine protein kinase inhibitor | 豪夫迈·罗氏有限公司 | 2017-12-22 | — | — | CN | disclosed |