Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.62 |
| ▸ | NOD2 | Q9HC29 | 5/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | CCR2 | P41597 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16794402 | 0.84 | NOD1 (0.71) | NOD1NOD2ALOX5CCR2ALDH1A1 | |
| SCHEMBL15520870 | 0.82 | HDAC3 (0.52) | NOD1NOD2ALOX5CCR2ALDH1A1 | |
| SCHEMBL28196444 | 0.79 | ALOX5 (0.63) | NOD1NOD2ALOX5CCR2ALDH1A1 | |
| SCHEMBL14627380 | 0.79 | NOD1 (0.78) | NOD1NOD2ALOX5CCR2ALDH1A1 | |
| SCHEMBL28414053 | 0.78 | NOD1 (0.61) | NOD1NOD2ALOX5ALDH1A1LMNA | |
| SCHEMBL30285319 | 0.77 | NOD1 (0.61) | NOD1NOD2ALOX5CCR2ALDH1A1 | |
| SCHEMBL3902283 | 0.77 | ALDH3A1 (0.58) | NOD1NOD2ALOX5ALDH1A1LMNA | |
| SCHEMBL29567743 | 0.77 | NOD2 (1.00) | NOD1NOD2ALOX5CCR2ALDH1A1 | |
| SCHEMBL6894539 | 0.77 | NOD2 (1.00) | NOD1NOD2ALOX5CCR2ALDH1A1 | |
| SCHEMBL28205246 | 0.76 | NOD1 (0.59) | NOD1NOD2ALOX5ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109134343-B | Method for alkenylating C-2 position of indole | 山东理工大学 | 2021-10-08 | — | — | CN | disclosed |
| CN-109134343-A | A kind of new method of the position indoles C-2 alkenyl | 山东理工大学 | 2019-01-04 | — | — | CN | disclosed |
| US-5166204-A | ISOINDOLE DERIVATIVES AND SALTS THEREOF AND ANTITUMOR AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |