Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.65 |
| ▸ | HTR1A | P08908 | 4/20 | 0.65 |
| ▸ | HTR2A | P28223 | 4/20 | 0.65 |
| ▸ | HTR5A | P47898 | 2/20 | 0.65 |
| ▸ | NCF1 | P14598 | 2/20 | 0.65 |
| ▸ | HTR3A | P46098 | 2/20 | 0.65 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.65 |
| ▸ | HTR3B | O95264 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | HTR1D | P28221 | 1/20 | 0.65 |
| ▸ | HTR1B | P28222 | 1/20 | 0.65 |
| ▸ | HTR7 | P34969 | 1/20 | 0.65 |
| ▸ | MTOR | P42345 | 1/20 | 0.65 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.65 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7687000 | 0.95 | HTR6 (0.63) | HTR6HTR1AHTR2AHTR5ANCF1 | |
| SCHEMBL4765551 | 0.90 | HTR6 (0.80) | HTR6HTR1AHTR2AHTR5ANCF1 | |
| SCHEMBL7719591 | 0.87 | HTR6 (0.87) | HTR6HTR1AHTR2AHTR5ANCF1 | |
| SCHEMBL1876619 | 0.80 | NCF1 (0.69) | HTR6HTR1AHTR2AHTR5ANCF1 | |
| SCHEMBL569714 | 0.80 | HTR1A (0.69) | HTR6HTR1AHTR2AHTR5ANCF1 | |
| SCHEMBL29385724 | 0.79 | HTR6 (1.00) | HTR6HTR1AHTR2AHTR5ANCF1 | |
| SCHEMBL240244 | 0.79 | HTR6 (1.00) | HTR6HTR1AHTR2AHTR5ANCF1 | |
| SCHEMBL3166780 | 0.79 | HTR6 (1.00) | HTR6HTR1AHTR2AHTR5ANCF1 | |
| SCHEMBL3080094 | 0.78 | NCF1 (0.67) | HTR6HTR1AHTR2AHTR5ANCF1 | |
| SCHEMBL7491687 | 0.78 | NCF1 (0.67) | HTR6HTR1AHTR2AHTR5ANCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107580598-A | Ethynyl derivatives serving as metabotropic glutamate receptor modulators | 豪夫迈·罗氏有限公司 | 2018-01-12 | — | — | CN | claimed |