SCHEMBL28197166

SCHEMBL28197166

CC(O)c1nccn1-c1ccc(Cl)cc1Cl

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.43
TSHR P16473 1/20 0.43
CYP2C19 P33261 1/20 0.43
HIF1A Q16665 1/20 0.43
KCNH2 Q12809 1/20 0.39
HCAR1 Q9BXC0 1/20 0.38
CYP11B2 P19099 1/20 0.37
GABRA2 P47869 2/20 0.36
GABRB2 P47870 2/20 0.36
ALDH1A1 P00352 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
EGLN2 Q96KS0 1/20 0.35
ADRA2C P18825 1/20 0.35
LMNA P02545 1/20 0.35
KMT2A Q03164 1/20 0.35
TLR8 Q9NR97 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11260141 0.74 KCNH2 (0.39) CYP2D6TSHRCYP2C19HIF1AKCNH2
SCHEMBL3491617 0.73 ALDH1A1 (0.41) CYP2D6TSHRCYP2C19HIF1AKCNH2
SCHEMBL8047156 0.73 HCAR1 (0.42) CYP2C19KCNH2HCAR1CYP11B2GABRA2
Nitric Acid SCHEMBL10469481 0.73 HIF1A (0.48) CYP2D6TSHRCYP2C19HIF1AGABRA2
SCHEMBL31376140 0.71 TLR8 (0.50) KCNH2HCAR1TLR8
SCHEMBL11967286 0.69 ALDH1A1 (0.39) CYP2D6TSHRCYP2C19HIF1AKCNH2
SCHEMBL11269224 0.68 GABRA2 (0.40) KCNH2HCAR1CYP11B2GABRA2GABRB2
SCHEMBL27805341 0.68 KCNH2 (0.38) CYP2D6TSHRCYP2C19HIF1AKCNH2
SCHEMBL5173711 0.67 IDO1 (0.49) CYP2D6TSHRCYP2C19KCNH2HCAR1
SCHEMBL28240610 0.67 KCNH2 (0.38) CYP2D6TSHRCYP2C19KCNH2HCAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109096197-A The synthesis technology of fenticonazole nitrate 翔宇药业股份有限公司 2018-12-28 CN disclosed
CN-107652238-A A kind of method of nitric acid synthesis Fenticonazole 翔宇药业股份有限公司 2018-02-02 CN disclosed
CN-107573288-A Process for refining, examination criteria and its application of fenticonazole nitrate 翔宇药业股份有限公司 2018-01-12 CN disclosed