Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27491044 | 0.81 | HAVCR2 (0.37) | HDAC1HDAC6FDPSMKNK2ALDH1A1 | |
| SCHEMBL2429098 | 0.81 | CYP1A2 (0.41) | HDAC1HDAC6FDPSALDH1A1LMNA | |
| SCHEMBL4409381 | 0.74 | NPC1 (0.41) | FDPSALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL28251675 | 0.71 | CYP1A2 (0.42) | ALDH1A1LMNACYP1A2CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL7659960 | 0.70 | CYP1A2 (0.41) | ALDH1A1LMNACYP1A2CYP3A4TSHR | |
| SCHEMBL3016798 | 0.69 | CA2 (0.43) | MEN1KMT2A | |
| SCHEMBL27337608 | 0.69 | HDAC1 (0.42) | HDAC1HDAC6FDPSMKNK2ALDH1A1 | |
| SCHEMBL5828209 | 0.69 | FDPS (0.40) | HDAC1HDAC6FDPSMKNK2ALDH1A1 | |
| SCHEMBL3421967 | 0.69 | FDPS (0.46) | HDAC1HDAC6FDPSMKNK2ALDH1A1 | |
| SCHEMBL3021750 | 0.69 | FDPS (0.40) | HDAC1HDAC6FDPSMKNK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107904201-A | Differentiation of the human embryo stem cell to pancreatic endocrine pedigree | 詹森生物科技公司 | 2018-04-13 | — | — | CN | claimed |
| CN-107904201-A | Differentiation of the human embryo stem cell to pancreatic endocrine pedigree | 詹森生物科技公司 | 2018-04-13 | — | — | CN | disclosed |
| CN-102272291-B | Differentiation of human embryonic stem cells into the pancreatic endocrine lineage | 詹森生物科技公司 | 2018-01-16 | — | — | CN | disclosed |