Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 10/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17247603 | 0.84 | MKNK1 (0.52) | CYP11B2CYP11B1CYP2A6FYNDYRK1A | |
| SCHEMBL21634194 | 0.69 | CYP2A6 (0.50) | CYP2A6FYNMKNK1MKNK2 | |
| SCHEMBL28197944 | 0.69 | PIK3CA (0.38) | FYNDYRK1AS1PR1 | |
| SCHEMBL5021553 | 0.68 | FDPS (0.57) | CYP11B2CYP11B1CYP2A6MKNK1MKNK2 | |
| SCHEMBL28855820 | 0.68 | CSNK1D (0.42) | FYNS1PR1 | |
| SCHEMBL2728918 | 0.67 | CYP2A6 (0.47) | CYP11B2CYP11B1CYP2A6DYRK1AMKNK1 | |
| SCHEMBL28197938 | 0.67 | P2RX7 (0.36) | S1PR1 | |
| SCHEMBL8336937 | 0.67 | CYP2A6 (0.54) | CYP11B2CYP11B1CYP2A6DYRK1A | |
| SCHEMBL18851872 | 0.66 | FYN (0.42) | FYN | |
| SCHEMBL844549 | 0.66 | MKNK1 (0.68) | CYP11B2CYP11B1CYP2A6FYNDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107667106-A | 2 (base of Pyrazolopyridine 3) pyrimidine derivatives as JAK inhibitor | 阿尔米雷尔有限公司 | 2018-02-06 | — | — | CN | disclosed |