SCHEMBL28200061

SCHEMBL28200061

O=C(O)CCCNC(O)(O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.48
SLC22A6 Q4U2R8 1/20 0.48
TSHR P16473 3/20 0.46
NFKB1 P19838 2/20 0.46
PMP22 Q01453 1/20 0.46
PRMT1 Q99873 1/20 0.43
GRIN2D O15399 1/20 0.42
GRIN3B O60391 1/20 0.42
GRIN1 Q05586 1/20 0.42
GRIN2A Q12879 1/20 0.42
GRIN2B Q13224 1/20 0.42
GRIN2C Q14957 1/20 0.42
GRIN3A Q8TCU5 1/20 0.42
CAMK2A Q9UQM7 1/20 0.42
ADRA1A P35348 1/20 0.40
GABRR3 A8MPY1 1/20 0.40
GABRP O00591 1/20 0.40
GABRD O14764 1/20 0.40
HDAC3 O15379 1/20 0.40
GABBR2 O75899 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7566798 0.82 LMNA (0.40) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL4806320 0.78 LMNA (0.46) LMNASLC22A6TSHRNFKB1PMP22
4-(Hydroxyamino)Butanoic Acid SCHEMBL1655977 0.76
SCHEMBL9979452 0.75 LMNA (0.42) LMNASLC22A6TSHRNFKB1PMP22
4-(Hydroxyamino)Butanoic Acid SCHEMBL28266183 0.74
SCHEMBL112741 0.73 LMNA (0.59) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL22653487 0.70
SCHEMBL11896840 0.70 LMNA (0.56) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL1741769 0.70 LMNA (0.56) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL31051705 0.70 PRMT1 (0.54) LMNASLC22A6TSHRNFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105153443-B Bioprotein two-dimensional nano-film prepared using lysozyme and preparation method thereof 陕西师范大学 2018-01-12 CN disclosed