Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.38 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | PPARD | Q03181 | 6/20 | 0.38 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4806320 | 0.82 | LMNA (0.46) | LMNASLC22A6ADRA1ATSHRNFKB1 | |
| SCHEMBL8591956 | 0.75 | LMNA (0.39) | LMNASLC22A6ADRA1ATSHRNFKB1 | |
| SCHEMBL28200061 | 0.75 | LMNA (0.48) | LMNASLC22A6ADRA1ATSHRNFKB1 | |
| SCHEMBL16491136 | 0.74 | ADRA1A (0.55) | LMNASLC22A6ADRA1ATSHRNFKB1 | |
| SCHEMBL13610844 | 0.74 | ADRA1A (0.55) | LMNASLC22A6ADRA1ATSHRNFKB1 | |
| SCHEMBL16908923 | 0.74 | CAMK2A (0.38) | LMNASLC22A6ADRA1ATSHRNFKB1 | |
| Pivagabine SCHEMBL96152 | 0.70 | POLB (0.53) | LMNASLC22A6ADRA1ATSHRPRMT1 | |
| SCHEMBL10247191 | 0.70 | LMNA (0.42) | LMNASLC22A6ADRA1ATSHRNFKB1 | |
| SCHEMBL22456219 | 0.69 | ADRA1A (0.50) | LMNASLC22A6ADRA1ATSHRNFKB1 | |
| SCHEMBL288681 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120111790-A1 | PREPARATION OF HIGH PERFORMANCE ULTRA FILTRATION HOLLOW FIBER MEMBRANE | BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT | 2012-05-10 | — | — | US | disclosed |
| US-8104624-B2 | Preparation of high performance ultra filtration hollow fiber membrane | AQUATECH INTERNATIONAL CORPORATION (US) | 2012-01-31 | — | — | US | disclosed |
| US-20090308805-A1 | PREPARATION OF HIGH PERFORMANCE ULTRA FILTRATION HOLLOW FIBER MEMBRANE | BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT | 2009-12-17 | — | — | US | disclosed |