Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | FEN1 | P39748 | 2/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL28072909 | 0.87 | TSHR (0.60) | TSHRFEN1ERCC5AKR1B1ALDH1A1 | |
| Bicarbonate SCHEMBL15402554 | 0.87 | TSHR (0.65) | TSHRFEN1ERCC5AKR1B1ALDH1A1 | |
| 1,2-Dichlorobenzene SCHEMBL28200711 | 0.84 | TSHR (0.56) | TSHRFEN1ERCC5AKR1B1ALDH1A1 | |
| Hydrazine SCHEMBL6210937 | 0.84 | PNMT (0.57) | TSHRALDH1A1KMT2AMEN1PNMT | |
| Glycolic Acid SCHEMBL27652059 | 0.83 | TSHR (0.56) | TSHRFEN1ERCC5AKR1B1ALDH1A1 | |
| Acetic Acid SCHEMBL6903660 | 0.82 | TSHR (0.60) | TSHRFEN1ERCC5AKR1B1ALDH1A1 | |
| SCHEMBL27775696 | 0.81 | ALDH1A1 (0.59) | TSHRFEN1ERCC5AKR1B1ALDH1A1 | |
| Hydrazine SCHEMBL28200710 | 0.81 | PNMT (0.55) | TSHRALDH1A1PNMTLMNA | |
| Benzene SCHEMBL28120498 | 0.81 | TSHR (0.58) | TSHRFEN1ERCC5AKR1B1ALDH1A1 | |
| Phosphoric Acid SCHEMBL28200096 | 0.80 | SMN1; SMN2 (0.50) | TSHRALDH1A1KMT2AMEN1PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107663161-B | Continuous flow synthesis process of phenylhydrazine salt and substituted phenylhydrazine salt | 上海惠和化德生物科技有限公司 | 2020-04-10 | — | — | CN | claimed |
| CN-107663161-B | Continuous flow synthesis process of phenylhydrazine salt and substituted phenylhydrazine salt | 上海惠和化德生物科技有限公司 | 2020-04-10 | — | — | CN | disclosed |
| CN-107663161-A | A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt | 上海惠和化德生物科技有限公司 | 2018-02-06 | — | — | CN | disclosed |