Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | BLM | P54132 | 3/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18731019 | 0.87 | HPRT1 (0.45) | LMNATSHRACHEKMT2AMEN1 | |
| SCHEMBL15896262 | 0.86 | ALDH1A1 (0.54) | LMNATSHRKMT2AMEN1RAB9A | |
| SCHEMBL313145 | 0.86 | ALDH1A1 (0.54) | LMNATSHRKMT2AMEN1RAB9A | |
| SCHEMBL25656541 | 0.81 | MAP4K4 (0.49) | LMNATSHRACHEKMT2AMEN1 | |
| SCHEMBL22181654 | 0.79 | ALDH1A1 (0.48) | LMNATSHRKMT2AMEN1RAB9A | |
| Toluene SCHEMBL7717685 | 0.78 | ACHE (0.71) | LMNATSHRACHEALOX12KMT2A | |
| SCHEMBL28478498 | 0.77 | ALDH1A1 (0.58) | TSHRKMT2AMEN1RAB9ANPC1 | |
| Toluene SCHEMBL28928389 | 0.77 | CASP1 (0.63) | LMNATSHRACHEALOX12KMT2A | |
| SCHEMBL22087616 | 0.77 | ACHE (0.60) | LMNATSHRACHEALOX12KMT2A | |
| Toluene SCHEMBL28825231 | 0.76 | ACHE (0.67) | LMNATSHRACHEALOX12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107663169-A | A kind of 6H naphtho-s [2,1,8,7 klmn] acridine derivatives and its application | 北京鼎材科技有限公司 | 2018-02-06 | — | — | CN | disclosed |