Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A known ✓ | Q99250 | 2/20 | 0.39 |
| ▸ | SCN10A known ✓ | Q9Y5Y9 | 2/20 | 0.39 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.38 |
| ▸ | SCN5A known ✓ | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A known ✓ | Q15858 | 1/20 | 0.38 |
| ▸ | SCN3A known ✓ | Q9NY46 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27123131 | 0.89 | ALDH1A1 (0.40) | P2RX1SCN2ASCN10ANPC1RAB9A | |
| Bromide SCHEMBL20984478 | 0.88 | ALDH1A1 (0.39) | P2RX1SCN2ASCN10ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL20984783 | 0.88 | ALDH1A1 (0.39) | P2RX1SCN2ASCN10ANPC1RAB9A | |
| Phosphoric Acid SCHEMBL20984546 | 0.88 | KMT2A (0.47) | P2RX1NPC1RAB9AKMT2ASMN1; SMN2 | |
| Oxalic Acid SCHEMBL28200785 | 0.87 | P2RX1 (0.41) | P2RX1SCN2ASCN10ANPC1RAB9A | |
| Sulfuric Acid SCHEMBL20984120 | 0.87 | TP53 (0.41) | P2RX1NPC1RAB9ALMNAKMT2A | |
| Nitric Acid SCHEMBL28200199 | 0.84 | KMT2A (0.38) | P2RX1NPC1RAB9ALMNANPSR1 | |
| Phosphoric Acid SCHEMBL20984697 | 0.80 | RAB9A (0.38) | NPC1RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL20984331 | 0.79 | P2RX1 (0.40) | P2RX1SCN2ASCN10ANPC1RAB9A | |
| SCHEMBL10988446 | 0.75 | ALDH1A1 (0.58) | NPC1RAB9ANPSR1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107663161-B | Continuous flow synthesis process of phenylhydrazine salt and substituted phenylhydrazine salt | 上海惠和化德生物科技有限公司 | 2020-04-10 | — | — | CN | claimed |
| CN-107663161-B | Continuous flow synthesis process of phenylhydrazine salt and substituted phenylhydrazine salt | 上海惠和化德生物科技有限公司 | 2020-04-10 | — | — | CN | disclosed |
| CN-107663161-A | A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt | 上海惠和化德生物科技有限公司 | 2018-02-06 | — | — | CN | disclosed |