Hydrazine

Hydrazine

SCHEMBL28200764

NN.O=S(=O)(O)Oc1c(F)cccc1F

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.37
CES1 P23141 2/20 0.37
PKM P14618 1/20 0.34
PKLR P30613 1/20 0.34
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
EPAS1 Q99814 1/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
BCHE P06276 1/20 0.33
SLC2A1 P11166 1/20 0.33
SLC2A4 P14672 1/20 0.33
KMT2A Q03164 1/20 0.33
CA12 O43570 1/20 0.33
FABP1 P07148 1/20 0.32
SLC6A2 P23975 1/20 0.32
IKBKB O14920 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28057527 0.80 ALB (0.50) CES2CES1BCHEKMT2A
Hydrazine SCHEMBL28200138 0.79 FABP1 (0.39) CES2CES1SLC22A6BCHEKMT2A
SCHEMBL19585795 0.78 CA2 (0.54) CA1CA2CA9
SCHEMBL26664898 0.76 ELANE (0.42) CES2CES1PKMPKLRCA1
SCHEMBL27962292 0.75 CES2 (0.33) CES2CES1PKMPKLREPAS1
SCHEMBL5016520 0.75 ALDH1A1 (0.44) PKMCA1CA2CA9
SCHEMBL14015391 0.74 CES2 (0.35) CES2CES1CA1CA2CA9
SCHEMBL3755699 0.74 PKM (0.36) CES2CES1PKMPKLREPAS1
SCHEMBL18632038 0.73 CES2 (0.41) CES2CES1PKMPKLRSLC22A6
SCHEMBL16070067 0.72 SLC22A6 (0.46) CES2CES1SLC22A6FABP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107663161-A A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt 上海惠和化德生物科技有限公司 2018-02-06 CN disclosed