Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8137804 | 0.75 | DRD4 (0.36) | CA2CA4CA1CA6DRD4 | |
| SCHEMBL4918423 | 0.72 | APEX1 (0.45) | CA2CA4DRD4APEX1 | |
| SCHEMBL1046753 | 0.72 | CYP3A4 (0.48) | CA2CA4CA1DRD4AKR1B1 | |
| SCHEMBL28417332 | 0.71 | DRD4 (0.39) | CA2CA4DRD4 | |
| SCHEMBL26334547 | 0.70 | TTR (0.31) | — | |
| SCHEMBL11446556 | 0.70 | DRD4 (0.58) | CA2CA4CA1CA6DRD4 | |
| SCHEMBL29121481 | 0.69 | APEX1 (0.40) | CA2CA4CA1CA6APEX1 | |
| SCHEMBL5419727 | 0.69 | CES2 (0.30) | DRD4 | |
| SCHEMBL10255927 | 0.68 | GAA (0.36) | CA1DRD4 | |
| SCHEMBL10796891 | 0.67 | CA2 (0.39) | CA2CA4CA1CA6APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107753468-B | Bis- (the bromo- 4,5- dihydroxy of 2,3,6- tri-) ethers are preparing the application in aldose reductase inhibitor product | 青岛大学 | 2019-08-02 | — | — | CN | disclosed |
| CN-107753468-A | Double (dihydroxy of 2,3,6 tribromo 4,5) applications of the ether in aldose reductase inhibitor product is prepared | 青岛大学 | 2018-03-06 | — | — | CN | disclosed |