SCHEMBL8137804

SCHEMBL8137804

OCc1c(Br)cc(Br)c(CBr)c1Br

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 1/20 0.36
CA2 P00918 2/20 0.32
CA4 P22748 2/20 0.32
CA1 P00915 1/20 0.32
CA6 P23280 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28200847 0.75 CA2 (0.40) DRD4CA2CA4CA1CA6
SCHEMBL2925270 0.73 ACHE (0.40)
SCHEMBL29121481 0.71 APEX1 (0.40) CA2CA4CA1CA6
SCHEMBL19270497 0.69 DRD4 (0.61) DRD4CA2CA4CA1CA6
SCHEMBL4918423 0.69 APEX1 (0.45) DRD4CA2CA4
SCHEMBL1046753 0.69 CYP3A4 (0.48) DRD4CA2CA4CA1
SCHEMBL11674685 0.68 CA1 (0.36) CA2CA4CA1CA6
SCHEMBL9850653 0.68 NQO2 (0.35) CA2CA4CA1CA6
SCHEMBL8126372 0.68 CYP3A4 (0.37)
SCHEMBL6131877 0.67 ERN1 (0.49) CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6156940-A Process for producing optically active carbinols SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) 2000-12-05 US disclosed
EP-0713848-B1 Process for producing optically active carbinols SUMIKA FINE CHEMICALS COMPANY (JP) 1999-09-08 EP disclosed
US-5831132-A REDUCING AGENT FROM BORANES AND AMINO ALCOHOLS SUMIKA FINE CHEMICALS COMPANY, LTD. (JP) 1998-11-03 US disclosed
EP-0713848-A1 Process for producing optically active carbinols SUMIKA FINE CHEMICALS Company, Limited (JP) 1996-05-29 EP disclosed