SCHEMBL8652157

SCHEMBL8652157

CCN(NC(N)=O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
GLA P06280 1/20 0.50
TSHR P16473 1/20 0.50
KDM4E B2RXH2 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
L3MBTL1 Q9Y468 1/20 0.43
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
NOX1 Q9Y5S8 1/20 0.42
TACR3 P29371 1/20 0.42
TP53 P04637 2/20 0.41
HPGD P15428 1/20 0.40
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11573258 0.83 TDP1 (0.40) ALDH1A1GLATSHRKDM4ETDP1
SCHEMBL9545457 0.82 ALDH1A1 (0.52) ALDH1A1GLATSHRKDM4ETDP1
SCHEMBL28146500 0.81 KDM4E (0.56) ALDH1A1GLAKDM4ETDP1MEN1
SCHEMBL11434297 0.81 ALDH1A1 (0.54) ALDH1A1GLATSHRKDM4EMTNR1A
SCHEMBL9446580 0.81 ALDH1A1 (0.51) ALDH1A1GLATSHRKDM4ETDP1
SCHEMBL11574181 0.80 BCAT2 (0.38) ALDH1A1GLATSHRKDM4ETDP1
SCHEMBL29137131 0.79 ALDH1A1 (0.48) ALDH1A1GLATSHRKDM4ETDP1
Alcohol SCHEMBL28831636 0.79 ALDH1A1 (0.50) ALDH1A1GLATSHRKDM4EMEN1
Water SCHEMBL28266025 0.79 ALDH1A1 (0.50) ALDH1A1GLATSHRKDM4ETDP1
SCHEMBL9134233 0.79 TDP1 (0.56) ALDH1A1GLATSHRKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113929866-B Modified resin and resin composition 旭化成株式会社 2023-07-07 CN disclosed
CN-111205424-B Modified resin and resin composition 旭化成株式会社 2022-04-08 CN disclosed
CN-113929866-A Modified resin and resin composition 旭化成株式会社 2022-01-14 CN disclosed
CN-107629183-B Modified resin and resin composition 旭化成株式会社 2021-01-05 CN disclosed
CN-111205424-A Modified resin and resin composition 旭化成株式会社 2020-05-29 CN disclosed
CN-105358602-B modified resin and resin composition 旭化成株式会社 2018-12-04 CN disclosed
CN-107629183-A Modified resin and resin combination 旭化成株式会社 2018-01-26 CN disclosed
US-5770692-A METHOD OF INTRODUCING UREIDO GROUPS INTO PEPTIDES WHILE PRESERVING STEREOCHEMISTRY PEPTISYNTHA (BE) 1998-06-23 US disclosed
EP-0562659-B1 Process to synthetise peptides and new intermediates thereof SOLVAY (BE) 1997-12-17 EP disclosed
CN-1097417-A New heterogeneous ring compound FUJISAWA PHARMACEUTICAL CO (JP) 1995-01-18 CN disclosed
EP-0562659-A1 Process to synthetise peptides and new intermediates thereof SOLVAY (Société Anonyme) (BE) 1993-09-29 EP disclosed