Benzamide

Benzamide

SCHEMBL8459253

C=Cc1ccccc1.NC(=O)c1ccccc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.67
TSHR P16473 3/20 0.67
RECQL P46063 2/20 0.67
PARP1 P09874 2/20 0.67
POLB P06746 1/20 0.67
CYP3A4 P08684 1/20 0.67
CYP2C19 P33261 1/20 0.67
BLM P54132 1/20 0.67
PMP22 Q01453 1/20 0.67
HSD17B10 Q99714 1/20 0.67
TDP1 Q9NUW8 1/20 0.67
L3MBTL1 Q9Y468 1/20 0.67
ALDH1A1 P00352 3/20 0.58
AKT1 P31749 1/20 0.48
PARP10 Q53GL7 3/20 0.47
PLA2G10 O15496 1/20 0.47
PLA2G2A P14555 1/20 0.47
HDAC2 Q92769 1/20 0.44
LMNA P02545 2/20 0.44
AKR1C1 Q04828 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalamide SCHEMBL28201048 0.96 TSHR (0.60) MAPTTSHRRECQLPARP1POLB
Styrene SCHEMBL5164588 0.87 ALDH1A1 (0.70) MAPTTSHRRECQLPARP1POLB
Styrene SCHEMBL2033347 0.87 ALDH1A1 (0.70) MAPTTSHRRECQLPARP1POLB
SCHEMBL1051273 0.85 ALDH1A1 (0.52) MAPTTSHRRECQLPARP1POLB
Styrene SCHEMBL27496207 0.85 ALDH1A1 (0.67) MAPTTSHRRECQLPARP1POLB
Styrene SCHEMBL27925811 0.85 ALDH1A1 (0.67) MAPTTSHRRECQLPARP1POLB
Benzamide SCHEMBL29082718 0.85 PARP1 (0.76) MAPTTSHRRECQLPARP1POLB
Benzophenone SCHEMBL28767057 0.83 ALDH1A1 (0.64) MAPTTSHRRECQLTDP1L3MBTL1
Benzil SCHEMBL5013455 0.83 CES2 (0.64) MAPTTSHRRECQLALDH1A1AKT1
Benzoic Acid SCHEMBL385226 0.83 ALDH1A1 (0.64) MAPTTSHRRECQLTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0315716-B1 METHOD OF MAKING A DIASTEREOMERIC MIXTURE CONTAINING TWO DIASTEREOMERIC N-ACYL-AMINO ACID ESTERS THE STANDARD OIL COMPANY (US) 1992-09-02 EP claimed
US-4721803-A Method of making a diastereomeric mixture containing two diastereomeric N-acyl-amino acid esters THE STANDARD OIL COMPANY (US) 1988-01-26 US claimed
US-5886217-A CATALYTIC HYDROGENATION TO FORM AN OPTICAL ACTIVE MATERIAL DEGUSSA AKTIENGESELLSCHAFT (DE) 1999-03-23 US disclosed
EP-0315716-B1 METHOD OF MAKING A DIASTEREOMERIC MIXTURE CONTAINING TWO DIASTEREOMERIC N-ACYL-AMINO ACID ESTERS THE STANDARD OIL COMPANY (US) 1992-09-02 EP disclosed
EP-0145265-B1 ALPHA-AMINO ACIDS THROUGH CATALYTIC REACTION OF CO AND A HYDROXYL COMPOUND WITH ENAMIDES THE STANDARD OIL COMPANY (US) 1989-09-20 EP disclosed
EP-0315716-A1 Method of making a diastereomeric mixture containing two diastereomeric N-acyl-amino acid esters THE STANDARD OIL COMPANY (US) 1989-05-17 EP disclosed
US-4749786-A α-amino acids through catalytic reaction of CO and a hydroxyl compound with enamides THE STANDARD OIL COMPANY (US) 1988-06-07 US disclosed
US-4721803-A Method of making a diastereomeric mixture containing two diastereomeric N-acyl-amino acid esters THE STANDARD OIL COMPANY (US) 1988-01-26 US disclosed
US-4710574-A HYDROCARBOXYLATION OF UNSATURATED AMIDES THE STANDARD OIL COMPANY (US) 1987-12-01 US disclosed
EP-0145265-A2 Alpha-amino acids through catalytic reaction of CO and a hydroxyl compound with enamides THE STANDARD OIL COMPANY (US) 1985-06-19 EP disclosed