Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 4/20 | 0.38 |
| ▸ | BPTF | Q12830 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 5/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18064932 | 0.86 | LMNA (0.51) | LMNACXCR4HTR6SIGMAR1GNAI3 | |
| SCHEMBL28200829 | 0.77 | CXCR4 (0.34) | LMNACXCR4BPTFSIGMAR1CYP1A2 | |
| SCHEMBL18064753 | 0.72 | LMNA (0.39) | LMNACXCR4HTR6CYP1A2CHRM2 | |
| SCHEMBL28167634 | 0.72 | HTR1A (0.46) | HTR6SIGMAR1CYP1A2SLC6A4ALDH1A1 | |
| SCHEMBL21799472 | 0.70 | LMNA (0.62) | LMNACXCR4HTR6SIGMAR1GNAI3 | |
| SCHEMBL29922612 | 0.70 | LMNA (0.62) | LMNACXCR4HTR6SIGMAR1GNAI3 | |
| SCHEMBL18064813 | 0.69 | ALDH1A1 (0.42) | LMNAATMSLC6A4ALDH1A1 | |
| SCHEMBL18064812 | 0.69 | ALDH1A1 (0.42) | LMNAATMSLC6A4ALDH1A1 | |
| SCHEMBL18064908 | 0.69 | PLA2G7 (0.46) | CXCR4SIGMAR1ATMALDH1A1 | |
| SCHEMBL18064906 | 0.69 | PLA2G7 (0.46) | CXCR4SIGMAR1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107660199-A | Piperazine carbamate and its preparation and application | 阿比德治疗公司 | 2018-02-02 | — | — | CN | disclosed |