Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | SOD1 | P00441 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL313756 | 0.87 | — | — | |
| SCHEMBL4584905 | 0.80 | DAO (0.45) | ALDH1A1DAOGPR84 | |
| SCHEMBL17241252 | 0.80 | ALDH1A1 (0.39) | ALDH1A1DAOCA2SMN1; SMN2 | |
| SCHEMBL17241205 | 0.80 | ALDH1A1 (0.43) | ALDH1A1DAOMGLLSMN1; SMN2 | |
| SCHEMBL12844536 | 0.75 | GPR84 (0.42) | ALDH1A1MGLLPLK1GPR84CA2 | |
| SCHEMBL2491352 | 0.75 | TP53 (0.56) | ALDH1A1PLK1CA2SMN1; SMN2 | |
| SCHEMBL178440 | 0.73 | LOXL2 (0.41) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL18617535 | 0.72 | PLK1 (0.50) | ALDH1A1PLK1 | |
| SCHEMBL3173022 | 0.71 | SAE1 (0.54) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL28201452 | 0.71 | SMN1; SMN2 (0.38) | ALDH1A1PLK1CA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214471-B | The preparation method of compound with Na-dependent glucose transporter inhibitory activity | 田边三菱制药株式会社 | 2018-02-06 | — | — | CN | disclosed |
| CN-104109155-A | Novel compounds | TANABE SEIYAKU CO | 2014-10-22 | — | — | CN | disclosed |
| CN-103819465-A | Novel compound | MITSUBISHI TANABE PHARMA CORP | 2014-05-28 | — | — | CN | disclosed |
| CN-103214471-A | Novel compound | MITSUBISHI TANABE PHARMA CORP | 2013-07-24 | — | — | CN | disclosed |
| CN-1829729-A | Novel compounds | TANABE SEIYAKU CO (JP) | 2006-09-06 | — | — | CN | disclosed |