⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28201447 | 0.87 | ALDH1A1 (0.39) | — | |
| SCHEMBL12844536 | 0.82 | GPR84 (0.42) | — | |
| SCHEMBL7238341 | 0.77 | HRH3 (0.50) | — | |
| SCHEMBL19476289 | 0.77 | PARP1 (0.39) | — | |
| SCHEMBL7466221 | 0.77 | MAPT (0.51) | — | |
| SCHEMBL524391 | 0.76 | — | — | |
| SCHEMBL1160586 | 0.76 | — | — | |
| SCHEMBL6931003 | 0.76 | — | — | |
| SCHEMBL18616803 | 0.76 | — | — | |
| SCHEMBL12122296 | 0.76 | ESR1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012107831-A1 | METHOD OF MAKING A PYRIDONE COMPOUND, 5-ETHYL-1-PHENYL-2-(1H)-PYRIDONE, AND INTERMEDIATES THEREOF | SIGNA S.A. DE C.V. (MX) | 2012-08-16 | — | — | WO | claimed |
| EP-2262501-A2 | TREATMENT OF SEPSIS WITH 5-ETHYL-1-PHENYL-2(1H)-PYRIDONE AND NOVEL METHODS FOR SYNTHESIS | Solanan, Inc. (US) | 2010-12-22 | — | — | EP | claimed |
| WO-2009111785-A2 | TREATMENT OF SEPSIS WITH 5-ETHYL-1-PHENYL-2(1H)-PYRIDONE AND NOVEL METHODS FOR SYNTHESIS | SOLANAN, INC. (US) | 2009-09-11 | — | — | WO | claimed |
| US-20260062393-A1 | Compounds | CTXT PTY LTD (AU) | 2026-03-05 | — | — | US | disclosed |
| US-12365655-B2 | Compounds | CTXT PTY LTD (AU) | 2025-07-22 | — | — | US | disclosed |
| CN-112334466-B | Compounds of formula (I) | CTXT私人有限公司 | 2025-05-30 | — | — | CN | disclosed |
| US-12043607-B2 | HDAC inhibitors and therapeutic use thereof | TANGO THERAPEUTICS, INC. (US) | 2024-07-23 | — | — | US | disclosed |
| WO-2024151833-A1 | SPIRO DERIVATIVES AS M4 ACTIVATORS/MODULATORS AND USES THEREOF | CEREVEL THERAPEUTICS, LLC (US) | 2024-07-18 | — | — | WO | disclosed |
| WO-2024059665-A1 | DIMERIC COMPOUNDS AS INHIBITORS OF GLYCOGEN SYNTHASE 1 (GYS1) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2024-03-21 | — | — | WO | disclosed |
| EP-4335439-A2 | COMPOUNDS | CTXT PTY LTD (AU) | 2024-03-13 | — | — | EP | disclosed |
| WO-2023239941-A1 | IMIDAZO(1,2-A)PYRIDINE DERIVATIVES AS RIPK2 INHIBITORS | INTERLINE THERAPEUTICS INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| EP-0843663-A1 | 4-ARYL-THIO-PYRIDIN-2(1H)-ONES, DRUGS CONTAINING SAME, AND USES THEREOF FOR TREATING HIV-RELATED DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1998-05-27 | — | — | EP | disclosed |
| EP-0813608-A1 | OSMIUM-CONTAINING REDOX MEDIATOR | BOEHRINGER MANNHEIM CORPORATION (US) | 1997-12-29 | — | — | EP | disclosed |
| WO-1997005113-A1 | 4-ARYL-THIO-PYRIDIN-2(1H)-ONES, DRUGS CONTAINING SAME, AND USES THEREOF FOR TREATING HIV-RELATED DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1997-02-13 | — | — | WO | disclosed |
| US-5589326-A | FOR ELECTROCHEMICAL BIOSENSORS | BOEHRINGER MANNHEIM CORPORATION (US) | 1996-12-31 | — | — | US | disclosed |
| WO-1996025514-A1 | OSMIUM-CONTAINING REDOX MEDIATOR | BOEHRINGER MANNHEIM CORPORATION (US) | 1996-08-22 | — | — | WO | disclosed |
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |
| US-4052509-A | 5-METHYL-1-PHENYL-2-(1H)-PYRIDONE | AFFILIATED MEDICAL RESEARCH, INC. (US) | 1977-10-04 | — | — | US | disclosed |
| US-4042699-A | 5-METHYL-1-PHENYL-2-(1H)-PYRIDONE | AFFILIATED MEDICAL RESEARCH, INC. (US) | 1977-08-16 | — | — | US | disclosed |
| US-3974281-A | ANALGESICS, ANTI-PYRETIC AND ANTI-INFLAMMATORY AGENTS | AFFILIATED MEDICAL RESEARCH, INC. (US) | 1976-08-10 | — | — | US | disclosed |