SCHEMBL28201480

SCHEMBL28201480

NS(=O)(=O)c1ccc(NCO)cc1

nearest known ligand 0.61

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA1 P00915 17/20 0.61
CA2 P00918 17/20 0.61
CA12 O43570 14/20 0.61
CA9 Q16790 13/20 0.61
CA4 P22748 2/20 0.57
CA6 P23280 2/20 0.57
CA5A P35218 2/20 0.57
CA7 P43166 2/20 0.57
CA14 Q9ULX7 2/20 0.57
CA5B Q9Y2D0 2/20 0.57
KMT2A Q03164 2/20 0.57
MEN1 O00255 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27540686 0.84 CA2 (0.62) CA1CA2CA12CA9CA4
SCHEMBL8637752 0.82 CA1 (0.68) CA1CA2CA12CA9CA4
Sulfuric Acid SCHEMBL28952576 0.81 CA2 (0.59) CA1CA2CA12CA9CA4
SCHEMBL21589347 0.81 LMNA (0.48) CA1CA2CA12CA9KMT2A
Mesulfamide SCHEMBL2110450 0.80 CA2 (0.58) CA1CA2CA12CA9CA4
SCHEMBL5803415 0.79 CA2 (0.65) CA1CA2CA12CA9CA4
SCHEMBL27936984 0.79 CA2 (0.67) CA1CA2CA12CA9CA4
SCHEMBL19985755 0.79 ALDH1A1 (0.43) CA1CA2CA12CA9CA5A
SCHEMBL27364275 0.79 CA2 (0.61) CA1CA2CA12CA9CA4
SCHEMBL6001822 0.78 CA1 (0.59) CA1CA2CA12CA9CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105294576-B A kind of preparation method of 6 methoxy pyrimidine sodium of sulfanilamide (SN) 和夏化学(太仓)有限公司 2018-04-13 CN disclosed