SCHEMBL8637752

SCHEMBL8637752

NS(=O)(=O)c1ccc(NCC(=O)O)cc1

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 18/20 0.68
CA2 P00918 18/20 0.68
CA12 O43570 12/20 0.68
CA9 Q16790 8/20 0.68
CA14 Q9ULX7 2/20 0.68
CA4 P22748 1/20 0.58
CA7 P43166 4/20 0.57
KMT2A Q03164 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15067141 0.83 CA1 (0.49) CA1CA2CA12CA9CA14
SCHEMBL28201480 0.82 CA1 (0.61) CA1CA2CA12CA9CA14
SCHEMBL27536397 0.82 CA1 (0.70) CA1CA2CA12CA9CA14
SCHEMBL5692310 0.82 ALDH1A1 (0.44) CA1CA2CA12CA9CA14
SCHEMBL24035204 0.81 TGM2 (0.49) CA1CA2CA12CA9CA14
Sulfamide SCHEMBL9565960 0.81 CA2 (0.53) CA1CA2CA12CA9CA14
Acediasulfone SCHEMBL143660 0.81 CYP2C19 (0.57) CA1CA2CA12CA9CA14
SCHEMBL4464115 0.80 CA1 (0.68) CA1CA2CA12CA9CA14
Acediasulfone SCHEMBL6656166 0.80 CYP2C19 (0.55) CA1CA2CA12CA9CA14
SCHEMBL27753685 0.77 ALDH1A1 (0.57) CA1CA2CA12CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4946761-A POLYMER CONTAINING CARBOXYL END GROUPS FUJI PHOTO FILM CO., LTD. (JP) 1990-08-07 US claimed
EP-0458485-B1 Image forming layer FUJI PHOTO FILM CO LTD (JP) 1998-07-29 EP disclosed
US-5395733-A Unsaturated polymer layer that can be decarboxylated on exposure to light and sensitizers FUJI PHOTO FILM CO., LTD. (JP) 1995-03-07 US disclosed
EP-0458485-A2 Image forming layer Fuji Photo Film Co., Ltd. (JP) 1991-11-27 EP disclosed
US-4946761-A POLYMER CONTAINING CARBOXYL END GROUPS FUJI PHOTO FILM CO., LTD. (JP) 1990-08-07 US disclosed
US-4405705-A HYDROPHILIC TOYO BOSEKI KABUSHIKI KAISHA T/A TOYOBA CO., LTD. (JP) 1983-09-20 US disclosed