Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | CFD | P00746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13577866 | 0.79 | LOXL2 (0.62) | LOXL2ENPP2ALDH1A1KMT2AHTR2C | |
| SCHEMBL8335580 | 0.79 | NPC1 (0.58) | ALDH1A1KMT2AMEN1MAPTTDP1 | |
| SCHEMBL28201097 | 0.78 | LOXL2 (0.59) | LOXL2ENPP2ALDH1A1HTR2CCFD | |
| SCHEMBL509423 | 0.77 | LOXL2 (0.66) | LOXL2ENPP2MAPTCFDTDP1 | |
| SCHEMBL29364575 | 0.77 | LOXL2 (0.66) | LOXL2ENPP2MAPTCFDTDP1 | |
| SCHEMBL8592573 | 0.77 | L3MBTL1 (0.56) | ALDH1A1HTTKMT2AMEN1MAPT | |
| SCHEMBL28879863 | 0.76 | LOXL2 (0.57) | LOXL2ENPP2ALDH1A1HTR2CCFD | |
| SCHEMBL28879968 | 0.76 | LOXL2 (0.57) | LOXL2ENPP2HTR2CCFDNOS1 | |
| SCHEMBL2643707 | 0.76 | LOXL2 (0.62) | LOXL2ENPP2ALDH1A1HTR2CMAPT | |
| SCHEMBL27280115 | 0.76 | LOXL2 (0.57) | LOXL2ENPP2HTR2CCFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107793374-A | A kind of preparation method of 2 bromine 1 (3 methoxyphenyl) oxazoles | 湖南华腾制药有限公司 | 2018-03-13 | — | — | CN | disclosed |