Known targets — ChEMBL curated mechanism
BTKCACNA1CCACNA1DCACNA1FCACNA1SCACNA2D1CACNA2D2DRD2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQHRH1HTR2AP2RY12
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL232168 | 0.98 | TSHR (0.67) | TSHRSMN1; SMN2POLBCYP2D6TP53 | |
| Isopropyl Alcohol SCHEMBL5735328 | 0.87 | TSHR (0.76) | TSHRSMN1; SMN2POLBCYP2D6LMNA | |
| SCHEMBL16046756 | 0.85 | TSHR (0.73) | TSHRSMN1; SMN2POLBCYP2D6LMNA | |
| Alanine SCHEMBL10626231 | 0.84 | TSHR (0.64) | TSHRSMN1; SMN2POLBCYP2D6MAPK1 | |
| Alanine SCHEMBL10627958 | 0.84 | TSHR (0.64) | TSHRSMN1; SMN2POLBCYP2D6MAPK1 | |
| SCHEMBL28902110 | 0.83 | TSHR (0.70) | TSHRSMN1; SMN2POLBCYP2D6LMNA | |
| Cadaverine Tartrate SCHEMBL231944 | 0.83 | TSHR (0.70) | TSHRSMN1; SMN2POLBCYP2D6LMNA | |
| SCHEMBL5875401 | 0.83 | TSHR (0.70) | TSHRSMN1; SMN2POLBCYP2D6LMNA | |
| Hydrochloric Acid SCHEMBL11436657 | 0.82 | TSHR (0.94) | TSHRSMN1; SMN2POLBCYP2D6LMNA | |
| Hydrochloric Acid SCHEMBL11436653 | 0.82 | TSHR (0.94) | TSHRSMN1; SMN2POLBCYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107698461-A | A kind of method for synthesizing cyhalofop-butyl | 连云港世杰农化有限公司 | 2018-02-16 | — | — | CN | disclosed |