Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | EPRS1 | P07814 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.49 |
| ▸ | CFD | P00746 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.47 |
| ▸ | ALAD | P13716 | 1/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27786187 | 0.82 | PTPN1 (0.58) | MCL1AKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL28201890 | 0.81 | TDP1 (0.53) | RXFP1MCL1AKR1C2AKR1C1KDM4E | |
| SCHEMBL27808113 | 0.81 | BCL2L1 (0.53) | RXFP1MCL1AKR1C2AKR1C1KDM4E | |
| SCHEMBL28026029 | 0.81 | AKR1C2 (0.56) | MCL1AKR1C2AKR1C1ALADMYC | |
| SCHEMBL28201920 | 0.80 | AKR1C2 (0.48) | MCL1CFDAKR1C2AKR1C1AKR1C4 | |
| SCHEMBL27556655 | 0.79 | AKR1C3 (0.56) | RXFP1CFDAKR1C2AKR1C1AKR1C4 | |
| Bromobenzene SCHEMBL27997726 | 0.78 | AKR1C3 (0.51) | RXFP1AKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL3467831 | 0.76 | PTPN1 (0.51) | MCL1AKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL27557477 | 0.76 | RXFP1 (0.50) | RXFP1EPRS1MCL1CFDMYC | |
| SCHEMBL28201887 | 0.75 | RXRA (0.55) | RXFP1MCL1CFDAKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105164113-B | Pyrroloamide inhibitors | 艾伯维公司 | 2018-03-02 | — | — | CN | disclosed |