SCHEMBL28202043

SCHEMBL28202043

O=C(O)c1cc2cccc(C(=O)O)c2nc1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.49
NR4A1 P22736 1/20 0.46
NR4A2 P43354 1/20 0.46
NR4A3 Q92570 1/20 0.46
KDM4E B2RXH2 4/20 0.44
ALOX15 P16050 2/20 0.44
MAPT P10636 2/20 0.44
HSD17B10 Q99714 2/20 0.44
CYP3A4 P08684 1/20 0.44
TSHR P16473 1/20 0.44
BLM P54132 1/20 0.44
AGER Q15109 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
GRIN2D O15399 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43
PTPN1 P18031 1/20 0.43
IDO1 P14902 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2804814 0.84 KDM4E (0.45) ALDH1A1KDM4EMAPTHSD17B10GRIN2D
SCHEMBL14678041 0.80 KEAP1 (0.49) ALDH1A1NR4A1NR4A2NR4A3KDM4E
SCHEMBL8806687 0.78 ALDH1A1 (0.58) ALDH1A1KDM4EALOX15MAPTCYP3A4
SCHEMBL31179778 0.78 ALDH1A1 (0.58) ALDH1A1KDM4EALOX15MAPTCYP3A4
SCHEMBL27991752 0.77 ALDH1A1 (0.56) ALDH1A1KDM4EALOX15MAPTHSD17B10
SCHEMBL27940676 0.77 ALDH1A1 (0.56) ALDH1A1KDM4EALOX15MAPTHSD17B10
SCHEMBL6579790 0.76 ALDH1A1 (0.47) ALDH1A1NR4A1NR4A2NR4A3KDM4E
SCHEMBL902623 0.76 ALDH1A1 (0.66) ALDH1A1NR4A1NR4A2NR4A3KDM4E
SCHEMBL70017 0.76 ALDH1A1 (0.61) ALDH1A1KDM4EMAPTTSHRPTPN1
SCHEMBL30034075 0.76 ALDH1A1 (0.61) ALDH1A1KDM4EMAPTTSHRPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107549871-A It is a kind of to eliminate composition of harmful substance and application thereof in cigarette or air 重庆市江北区健希环保新材料科技有限公司 2018-01-09 CN disclosed