Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5833104 | 0.87 | GPR119 (0.31) | — | |
| SCHEMBL2820048 | 0.83 | MMP13 (0.37) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL2823045 | 0.80 | KMT2A (0.33) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2823211 | 0.80 | LMNA (0.38) | ALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL2820325 | 0.79 | TSHR (0.40) | ALDH1A1LMNAHPGD | |
| SCHEMBL2820531 | 0.78 | OPRL1 (0.37) | — | |
| SCHEMBL2820985 | 0.78 | MMP13 (0.34) | ALDH1A1LMNAHPGD | |
| SCHEMBL2821657 | 0.77 | KDM4E (0.38) | ALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL2820199 | 0.77 | MMP13 (0.31) | — | |
| SCHEMBL2819552 | 0.76 | KDM4E (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1386914-B1 | HALOGENATED QUINOLINE DERIVATIVES AND ECTOPARASITE CONTROLLERS | MEIJI SEIKA KAISHA (JP) | 2010-10-27 | — | — | EP | disclosed |
| US-7022855-B2 | Halogen-substituted quinoline derivatives and ectoparasite control agent | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-04-04 | — | — | US | disclosed |