Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2820529 | 0.80 | ALDH1A1 (0.30) | LMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL2820533 | 0.79 | L3MBTL1 (0.34) | LMNAHPGDSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2823212 | 0.77 | SCN9A (0.34) | LMNAHPGDSMN1; SMN2KDM4E | |
| SCHEMBL2819557 | 0.77 | HTT (0.35) | LMNAHPGDSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2820005 | 0.75 | ALDH1A1 (0.34) | LMNAHPGDSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2819564 | 0.73 | PTGS2 (0.37) | LMNAHPGDSMN1; SMN2ALDH1A1ACACB | |
| SCHEMBL2821666 | 0.72 | RAB9A (0.36) | LMNAHPGDSMN1; SMN2KDM4E | |
| SCHEMBL2823274 | 0.72 | DHODH (0.31) | HPGDALDH1A1KDM4E | |
| SCHEMBL2819998 | 0.71 | P2RX7 (0.32) | LMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL2821034 | 0.71 | PTGS2 (0.33) | LMNAHPGDSMN1; SMN2ACACBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1386914-B1 | HALOGENATED QUINOLINE DERIVATIVES AND ECTOPARASITE CONTROLLERS | MEIJI SEIKA KAISHA (JP) | 2010-10-27 | — | — | EP | disclosed |
| US-7022855-B2 | Halogen-substituted quinoline derivatives and ectoparasite control agent | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-04-04 | — | — | US | disclosed |