Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.44 |
| ▸ | GLMN | Q92990 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL138594 | 0.88 | EPHX2 (0.56) | EPHX2FAAHP2RX7MAPK1EPHX1 | |
| Hydrochloric Acid SCHEMBL27845477 | 0.86 | EPHX2 (0.54) | EPHX2FAAHP2RX7MAPK1EPHX1 | |
| SCHEMBL1397748 | 0.78 | EPHX2 (0.47) | EPHX2FAAHP2RX7MAPK1EPHX1 | |
| SCHEMBL11152183 | 0.76 | EPHX2 (0.53) | EPHX2FAAHP2RX7MAPK1EPHX1 | |
| Hydrochloric Acid SCHEMBL11156286 | 0.74 | EPHX2 (0.51) | EPHX2FAAHP2RX7MAPK1EPHX1 | |
| SCHEMBL26240819 | 0.71 | CNR2 (0.48) | EPHX2DPP8DPP9GLMNMAPK1 | |
| SCHEMBL1578125 | 0.69 | FAAH (0.81) | FAAHP2RX7EPHX1 | |
| SCHEMBL7980459 | 0.68 | EPHX2 (0.58) | EPHX2P2RX7EPHX1 | |
| SCHEMBL11447009 | 0.68 | POLB (0.53) | EPHX2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL26240827 | 0.67 | TRPV6 (0.47) | EPHX2DPP8DPP9GLMNP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107673977-A | A kind of preparation method of the aromatic diamine containing adamantane structure | 上海博栋化学科技有限公司 | 2018-02-09 | — | — | CN | disclosed |