SCHEMBL138594

SCHEMBL138594

c1ccc(NC23CC4CC(CC(C4)C2)C3)cc1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 10/20 0.56
FAAH O00519 1/20 0.50
P2RX7 Q99572 4/20 0.47
MAPK1 P28482 1/20 0.45
EPHX1 P07099 1/20 0.44
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42
ALOX12 P18054 1/20 0.42
HTT P42858 1/20 0.42
ATM Q13315 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
HSD17B10 Q99714 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27845477 0.98 EPHX2 (0.54) EPHX2FAAHP2RX7MAPK1EPHX1
SCHEMBL1397748 0.90 EPHX2 (0.47) EPHX2FAAHP2RX7MAPK1EPHX1
SCHEMBL28205291 0.88 EPHX2 (0.49) EPHX2FAAHP2RX7MAPK1EPHX1
SCHEMBL7980459 0.79 EPHX2 (0.58) EPHX2P2RX7EPHX1ALDH1A1TSHR
SCHEMBL11447009 0.79 POLB (0.53) EPHX2ALDH1A1TSHRHTTHSD17B10
SCHEMBL11152183 0.79 EPHX2 (0.53) EPHX2FAAHP2RX7MAPK1EPHX1
Hydrochloric Acid SCHEMBL11156286 0.78 EPHX2 (0.51) EPHX2FAAHP2RX7MAPK1EPHX1
SCHEMBL22441207 0.77 EPHX2 (0.68) EPHX2FAAHEPHX1
SCHEMBL7979165 0.77 EPHX2 (0.62) EPHX2P2RX7MAPK1EPHX1TSHR
SCHEMBL30208695 0.77 ALDH1A1 (0.43) EPHX2FAAHALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118064421-A Covalent organic framework material immobilized biocatalyst and preparation method and application thereof 南开大学 2024-05-24 CN claimed
CN-117143387-A Covalent organic framework material with structural color and preparation method thereof 中山大学 2023-12-01 CN claimed
CN-109897190-B N-heterocyclic carbene functionalized covalent organic framework material and synthesis method thereof 山西师范大学 2021-07-30 CN claimed
CN-108117513-B Three-dimensional bipyridyl functionalized organic porous material and synthesis method and application thereof 中国科学院大连化学物理研究所 2020-08-21 CN claimed
CN-107915658-B Three-dimensional covalent organic framework material based on adamantane unit and synthesis and application thereof 中国科学院大连化学物理研究所 2020-04-21 CN claimed
CN-108117537-B Three-dimensional covalent organic framework material based on tetrathiafulvalene unit and synthetic method 中国科学院大连化学物理研究所 2020-03-31 CN claimed
CN-110894321-A Preparation method of mildew-proof bamboo-plastic composite material 安徽霖园外新材料有限公司 2020-03-20 CN claimed
CN-108117646-B A kind of three-dimensional polyimides covalence organic porous material and its preparation method and application 中国科学院大连化学物理研究所 2019-11-08 CN claimed
CN-120483884-A Adamantyl aniline derivative and preparation method thereof 甘肃省天之河科技化工有限公司 2025-08-15 CN disclosed
CN-120483884-A Adamantyl aniline derivative and preparation method thereof 甘肃省天之河科技化工有限公司 2025-08-15 CN disclosed
CN-118344545-A Triphenylamine-based three-dimensional covalent organic framework material and preparation method and application thereof 安徽大学 2024-07-16 CN disclosed
CN-118064421-A Covalent organic framework material immobilized biocatalyst and preparation method and application thereof 南开大学 2024-05-24 CN disclosed
CN-117430766-A Biological composite material based on covalent organic framework materials (COFs), preparation and application thereof 南开大学 2024-01-23 CN disclosed
CN-117143387-A Covalent organic framework material with structural color and preparation method thereof 中山大学 2023-12-01 CN disclosed
US-20120059182-A1 Catalysts, Methods of Makting Catalysts, and Methods of Use UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2012-03-08 US disclosed
US-20110201665-A1 Compositions, Methods, and Kits for Treating Influenza Viral Infections COMBINATORX (SINGAPORE) PTE. LTD. (SG) 2011-08-18 US disclosed
US-20110028510-A1 Compositions, Methods, and Kits for Treating Influenza Viral Infections COMBINATORX (SINGAPORE) PTE. LTD. (SG) 2011-02-03 US disclosed
EP-0810223-B1 Adamantyl substituted oxindoles as pharmaceutical agents PFIZER (US) 2001-07-25 EP disclosed
US-5948781-A Adamantyl substituted oxindoles as pharmaceutical agents PFIZER INC (US) 1999-09-07 US disclosed
EP-0810223-A1 Adamantyl substituted oxindoles as pharmaceutical agents PFIZER INC. (US) 1997-12-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120059182-A1 Catalysts, Methods of Makting Catalysts, and Methods of Use DKC1, ADCK1, AMD1 EPHX2 1830/4885FAAH 1790/4885P2RX7 4847/4885
US-20110201665-A1 Compositions, Methods, and Kits for Treating Influenza Viral Infections IL5, CCL5, CCL11 EPHX2 1373/4885FAAH 1963/4885P2RX7 99/4885
US-20110028510-A1 Compositions, Methods, and Kits for Treating Influenza Viral Infections IL5, CCL5, CCL11 EPHX2 1373/4885FAAH 1963/4885P2RX7 99/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.