Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL138594 | 0.79 | EPHX2 (0.56) | EPHX2ALDH1A1HTTP2RX7TSHR | |
| SCHEMBL7979165 | 0.78 | EPHX2 (0.62) | EPHX2MEN1KMT2ACYP17A1CYP19A1 | |
| Hydrochloric Acid SCHEMBL27845477 | 0.78 | EPHX2 (0.54) | EPHX2ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL11447009 | 0.76 | POLB (0.53) | EPHX2ALDH1A1GAAHTTTSHR | |
| SCHEMBL21292856 | 0.72 | EPHX2 (0.45) | EPHX2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL21309807 | 0.72 | PGR (0.45) | EPHX2EPHX1 | |
| SCHEMBL3361761 | 0.72 | ALDH1A1 (0.63) | EPHX2ALDH1A1MEN1KMT2ACYP17A1 | |
| SCHEMBL1397748 | 0.71 | EPHX2 (0.47) | EPHX2ALDH1A1HTTP2RX7TSHR | |
| SCHEMBL22441207 | 0.71 | EPHX2 (0.68) | EPHX2MEN1KMT2AEPHX1 | |
| SCHEMBL7967017 | 0.71 | EPHX2 (0.42) | EPHX2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001074778-A1 | (1-ADAMANTYLAMINO)PYRIDINES AND METHOD OF THEIR PREPARATION | FUNDACJA ROZWOJU DIAGNOSTYKI I TERAPII (PL) | 2001-10-11 | — | — | WO | claimed |