Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 3/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28251018 | 0.90 | CTSK (0.52) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL3425339 | 0.87 | ATM (0.51) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL29077117 | 0.87 | ATM (0.51) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL2429231 | 0.87 | ACE (0.46) | ATMCTSSCTSKCTSLCTSB | |
| Water SCHEMBL27509393 | 0.86 | CTSS (0.51) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL27962225 | 0.82 | KLK5 (0.46) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL6345188 | 0.80 | CTSK (0.51) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL15514064 | 0.78 | SYK (0.53) | CTSSIDO1CA12CA1CA7 | |
| SCHEMBL7806363 | 0.78 | LTA4H (0.56) | PPARGPPARA | |
| SCHEMBL13816316 | 0.78 | SYK (0.56) | ATMCTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167921-A | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | 勃林格殷格翰动物保健美国公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-107835818-A | Anthelmintic depsipeptide compounds | 梅里亚股份有限公司 | 2018-03-23 | — | — | CN | disclosed |