Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOST | Q9BQB4 | 1/20 | 0.79 |
| ▸ | FPGS | Q05932 | 2/20 | 0.78 |
| ▸ | GART | P22102 | 5/20 | 0.59 |
| ▸ | DHFR | P00374 | 1/20 | 0.53 |
| ▸ | ATIC | P31939 | 2/20 | 0.51 |
| ▸ | MTHFD1 | P11586 | 2/20 | 0.49 |
| ▸ | NOS1 | P29475 | 2/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MTHFD2 | P13995 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50298 | 0.91 | SOST (0.78) | SOSTFPGSGARTDHFRATIC | |
| SCHEMBL15121249 | 0.91 | SOST (0.78) | SOSTFPGSGARTDHFRATIC | |
| SCHEMBL3953439 | 0.91 | SOST (0.78) | SOSTFPGSGARTDHFRATIC | |
| SCHEMBL716106 | 0.91 | SOST (0.78) | SOSTFPGSGARTDHFRATIC | |
| SCHEMBL27708884 | 0.90 | SOST (0.77) | SOSTFPGSGARTDHFRATIC | |
| SCHEMBL4126044 | 0.90 | SOST (0.77) | SOSTFPGSGARTDHFRATIC | |
| SCHEMBL28469783 | 0.90 | SOST (0.77) | SOSTFPGSGARTDHFRATIC | |
| Tetrahydrofolate SCHEMBL23630632 | 0.90 | SOST (0.92) | SOSTFPGSGARTDHFRATIC | |
| Tetrahydrofolate SCHEMBL4628326 | 0.90 | SOST (0.92) | SOSTFPGSGARTDHFRATIC | |
| Tetrahydrofolate SCHEMBL21248573 | 0.90 | SOST (0.92) | SOSTFPGSGARTDHFRATIC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107892692-A | The preparation method and applications of (6S) 5 methyl tetrahydrofolate zinc salt | 华东理工大学 | 2018-04-10 | — | — | CN | claimed |
| CN-107892692-A | The preparation method and applications of (6S) 5 methyl tetrahydrofolate zinc salt | 华东理工大学 | 2018-04-10 | — | — | CN | disclosed |
| CN-107892692-A | The preparation method and applications of (6S) 5 methyl tetrahydrofolate zinc salt | 华东理工大学 | 2018-04-10 | — | — | CN | disclosed |
| CN-107698591-A | (6S) -5-methyltetrahydrofolate zinc salt crystal formation and preparation method thereof | 上海华理生物医药有限公司 | 2018-02-16 | — | — | CN | disclosed |