Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOST | Q9BQB4 | 1/20 | 0.78 |
| ▸ | FPGS | Q05932 | 2/20 | 0.77 |
| ▸ | GART | P22102 | 5/20 | 0.58 |
| ▸ | DHFR | P00374 | 1/20 | 0.52 |
| ▸ | ATIC | P31939 | 4/20 | 0.51 |
| ▸ | MTHFD1 | P11586 | 1/20 | 0.51 |
| ▸ | NOS3 | P29474 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15121249 | 1.00 | SOST (0.78) | SOSTFPGSGARTDHFRATIC | |
| SCHEMBL3953439 | 1.00 | SOST (0.78) | SOSTFPGSGARTDHFRATIC | |
| SCHEMBL716106 | 1.00 | SOST (0.78) | SOSTFPGSGARTDHFRATIC | |
| SCHEMBL28469783 | 0.99 | SOST (0.77) | SOSTFPGSGARTDHFRATIC | |
| SCHEMBL27708884 | 0.99 | SOST (0.77) | SOSTFPGSGARTDHFRATIC | |
| SCHEMBL9485867 | 0.94 | SOST (0.74) | SOSTFPGSGARTDHFRATIC | |
| Water SCHEMBL9486835 | 0.93 | SOST (0.73) | SOSTFPGSGARTDHFRATIC | |
| Homocysteine SCHEMBL27706413 | 0.93 | SOST (0.70) | SOSTFPGSGARTDHFRATIC | |
| L-Homocysteine SCHEMBL1888976 | 0.93 | SOST (0.70) | SOSTFPGSGARTDHFRATIC | |
| Glutamic Acid SCHEMBL4628258 | 0.93 | SOST (0.80) | SOSTFPGSGARTDHFRATIC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1651 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12529078-B2 | Microorganisms and methods for improving product yields on methanol using acetyl-CoA synthesis | GENOMATICA, INC. (US) | 2026-01-20 | — | — | US | claimed |
| US-12264354-B2 | Microorganisms and methods for enhancing the availability of reducing equivalents in the presence of methanol, and for producing 1,4-butanediol related thereto | GENOMATICA, INC. (US) | 2025-04-01 | — | — | US | claimed |
| CN-118837462-B | Method for measuring 13 metabolism regulation core molecules under same chromatographic system and construction of detection discrimination model thereof | 上海交通大学医学院附属瑞金医院 | 2025-02-28 | — | — | CN | claimed |
| CN-118837462-A | Method for measuring 13 metabolism regulation core molecules under same chromatographic system and construction of detection discrimination model thereof | 上海交通大学医学院附属瑞金医院 | 2024-10-25 | — | — | CN | claimed |
| US-20240294950-A1 | MICROORGANISMS AND METHODS FOR IMPROVING PRODUCT YIELDS ON METHANOL USING ACETYL-COA SYNTHESIS | AGAIN BIO APS (DK) | 2024-09-05 | — | — | US | claimed |
| CN-113930374-B | Recombinant microorganism capable of growing using only carbon dioxide and formic acid and method for producing useful substance using the same | 韩国科学技术院 | 2024-08-27 | — | — | CN | claimed |
| CN-118048333-A | Methylene tetrahydrofolate dehydrogenase (MTHFD) and application thereof | 西北大学 | 2024-05-17 | — | — | CN | claimed |
| EP-3359138-B1 | DIETARY SUPPLEMENTATION TO ACHIEVE OXY-REDOX HOMEOSTASIS AND EPIGENETIC STABILITY | PARTHENOGEN SAGL (CH) | 2024-04-24 | — | — | EP | claimed |
| CN-110234766-B | Recombinant microorganism having foreign gene introduced therein and method for producing useful material from formic acid and carbon dioxide using the same | 韩国科学技术院 | 2024-02-27 | — | — | CN | claimed |
| CN-117402799-A | Recombinant cell, method for producing recombinant cell, and method for producing isoprene or terpene | 积水化学工业株式会社 | 2024-01-16 | — | — | CN | claimed |
| EP-1221615-A2 | S-adenosyl methionine regulation of metabolic pathways and its use in diagnosis and therapy | ORIDIGM CORPORATION (US) | 2002-07-10 | — | — | EP | claimed |
| WO-2001077367-A1 | RADIOENZYMATIC ASSAY FOR METHYLENETETRAHYDROFOLATE REDUCTASE | ROTHENBERG SHELDON P (US) | 2001-10-18 | — | — | WO | claimed |
| WO-2001056609-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING HYPERHOMOCYSTEINAEMIA CAUSED BY MEDICAMENTS | WESTPHAL SABINE (DE) | 2001-08-09 | — | — | WO | claimed |
| EP-0429611-B1 | AMINOALKYL MALEIMIDES AND HAPTENE AND ANTIGEN DERIVATIVES THEREOF AND CONJUGATES WITH PEPTIDES OR PROTEINS | ROCHE DIAGNOSTICS GMBH (DE) | 2001-02-28 | — | — | EP | claimed |
| US-6191133-B1 | MIXTURE OF SEROTONINE REUPTAKE INHIBITOR, NORADRENALINE REUPTAKE INHIBITOR AND FOLIC ACID | SCARISTA LIMITED (GB) | 2001-02-20 | — | — | US | claimed |
| US-6020139-A | S-adenosyl methionine regulation of metabolic pathways and its use in diagnosis and therapy | ORIDIGM CORPORATION (US) | 2000-02-01 | — | — | US | claimed |
| US-5350850-A | Process for the preparation of substituted tetrahydrofolico derivatives in the [6(R,S)(-)] forms and of their active [6(S)(-)] N5 diastereoisomers in form of alkali and alkaline earth metal salts | APR APPLIED PHARMA RESEARCH S.A. (CH) | 1994-09-27 | — | — | US | claimed |
| EP-0382019-B1 | USE OF 5-METHYLTETRAHYDROFOLIC ACID, OF 5-FORMYL-TETRAHYDROFOLIC ACID AND OF THEIR PHARMACEUTICALLY ACCEPTABLE SALTS FOR THE PREPARATION OF CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS SUITABLE FOR THE USE IN THE THERAPY OF DEPRESSIVE DISTURBANCES, AND PHARMACEUTICAL COMPOSITIONS THUS PREPARED | BIORESEARCH S.p.A. (IT) | 1993-05-05 | — | — | EP | claimed |
| EP-0537842-A2 | A process for the preparation of substituted tetrahydrofolic derivatives in the 6(R,S)(-) forms and of their active 6(S)(-) N5 diastereoisomers in form of alkali and earth alkali metal salts | APR APPLIED PHARMA RESEARCH S.A. (CH) | 1993-04-21 | — | — | EP | claimed |
| US-5124452-A | Reduction of folic acid; methylation separation; purification; reducing agent stabilizer | BIORESEARCH S.P.A. (IT) | 1992-06-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12529078-B2 | Microorganisms and methods for improving product yields on methanol using acetyl-CoA synthesis | ALDOA, FDPS, DERA | SOST 4415/4885FPGS 163/4885GART 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.