Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | KIF11 | P52732 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | LDHB | P07195 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.40 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19317476 | 0.87 | KDM4E (0.49) | KDM4EKIF11MEN1KMT2AALDH1A1 | |
| SCHEMBL28024557 | 0.84 | NR4A2 (0.49) | KDM4EKIF11MEN1KMT2AALDH1A1 | |
| SCHEMBL6824313 | 0.83 | MEN1 (0.56) | KDM4EKIF11MEN1KMT2AALDH1A1 | |
| SCHEMBL28206987 | 0.82 | KIF11 (0.47) | KDM4EKIF11MEN1KMT2AALDH1A1 | |
| SCHEMBL28207454 | 0.82 | MAP2 (0.47) | KDM4EMEN1KMT2AHPGDMAPT | |
| SCHEMBL28206996 | 0.81 | ALDH1A1 (0.53) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL28062757 | 0.81 | ALDH1A1 (0.42) | KDM4EKIF11MEN1KMT2AALDH1A1 | |
| SCHEMBL28062838 | 0.79 | KDM4E (0.40) | KDM4EKIF11MEN1KMT2AALDH1A1 | |
| SCHEMBL18932673 | 0.79 | ALDH1A1 (0.59) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL1115219 | 0.78 | L3MBTL1 (0.53) | MEN1KMT2APIN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104892485-B | 2 perfluoroalkyl indole derivativeses and its synthetic method | 上海麦克林生化科技有限公司 | 2018-03-23 | — | — | CN | disclosed |