Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.36 |
| ▸ | FLT1 | P17948 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28062889 | 0.90 | RAB9A (0.38) | KDM4EALDH1A1HPGDKIF11RAB9A | |
| SCHEMBL28206987 | 0.85 | KIF11 (0.47) | KDM4EALDH1A1HPGDTHRBKIF11 | |
| SCHEMBL28062757 | 0.81 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDKIF11PPARG | |
| SCHEMBL28207446 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1HPGDKIF11NPC1 | |
| SCHEMBL28062893 | 0.78 | KDM4E (0.48) | KDM4EALDH1A1HPGDRECQLRAB9A | |
| SCHEMBL6824313 | 0.77 | MEN1 (0.56) | KDM4EALDH1A1HPGDKIF11MEN1 | |
| SCHEMBL28206980 | 0.76 | RAB9A (0.52) | KDM4EALDH1A1HPGDTHRBKIF11 | |
| SCHEMBL28207454 | 0.76 | MAP2 (0.47) | KDM4EHPGDRXFP1MEN1KMT2A | |
| SCHEMBL28206996 | 0.76 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDTDP1RAB9A | |
| SCHEMBL28207487 | 0.74 | KIF11 (0.43) | KDM4EKIF11RAB9AFGFR1FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646327-A | 2-perfluoroalkyl indole derivative and synthesis method thereof | 上海大学 | 2016-06-08 | — | — | CN | disclosed |