Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8647207 | 0.81 | LTB4R (0.45) | LTB4RLTB4R2PSMB5DRD2DRD3 | |
| SCHEMBL10282172 | 0.81 | HTR2B (0.43) | LTB4RLTB4R2PSMB5DRD2DRD3 | |
| SCHEMBL6339887 | 0.81 | HTR1A (0.55) | LTB4RLTB4R2PSMB5DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL29960409 | 0.80 | HTR2C (0.54) | LTB4RLTB4R2PSMB5DRD2DRD3 | |
| SCHEMBL2316931 | 0.77 | LTB4R (0.47) | LTB4RLTB4R2PSMB5DRD2DRD3 | |
| SCHEMBL6099078 | 0.77 | LTB4R (0.47) | LTB4RLTB4R2PSMB5DRD2DRD3 | |
| SCHEMBL2688677 | 0.77 | LTB4R (0.44) | LTB4RLTB4R2PSMB5DRD2DRD3 | |
| SCHEMBL506552 | 0.77 | CYP2D6 (0.47) | LTB4RLTB4R2PSMB5DRD2DRD3 | |
| SCHEMBL2316932 | 0.77 | LTB4R (0.47) | LTB4RLTB4R2PSMB5DRD2DRD3 | |
| SCHEMBL19574896 | 0.77 | LTB4R (0.44) | LTB4RLTB4R2PSMB5DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120302566-A1 | INDANYLOXYDIHYDROBENZOFURANYLACETIC ACIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120302566-A1 | INDANYLOXYDIHYDROBENZOFURANYLACETIC ACIDS | GPR119, INSR, GPR52 | LTB4R 447/4885LTB4R2 236/4885PSMB5 3145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.