Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.66 |
| ▸ | ACHE | P22303 | 5/20 | 0.66 |
| ▸ | MAOA | P21397 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | CASP3 | P42574 | 2/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.52 |
| ▸ | TUBB | P07437 | 1/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550306 | 0.94 | MAOB (0.62) | MAOBACHEMAOAMEN1KMT2A | |
| SCHEMBL28209630 | 0.91 | CASP3 (0.61) | MAOBACHEMEN1KMT2AKDM4E | |
| SCHEMBL28411136 | 0.85 | CASP3 (0.57) | MAOBACHEMAOAMEN1KMT2A | |
| SCHEMBL30608274 | 0.84 | KDM4E (0.72) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL28402272 | 0.82 | NPC1 (0.51) | MAOBACHEMAOAMEN1KMT2A | |
| SCHEMBL8545664 | 0.82 | KDM4E (0.53) | MAOBACHEMAOAMEN1KMT2A | |
| SCHEMBL7432074 | 0.80 | ACHE (1.00) | MAOBACHEMAOA | |
| SCHEMBL28208744 | 0.79 | NPC1 (0.64) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL8437810 | 0.78 | KDM4E (0.62) | MAOBACHEMAOAMEN1KMT2A | |
| SCHEMBL720239 | 0.78 | CASP3 (0.70) | MAOBACHEMAOAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107827849-B | 6- [ 2-hydroxy-3- (alkylamino) propoxy ] benzofuran compound and application thereof | 沈阳药科大学 | 2020-06-02 | — | — | CN | disclosed |
| CN-107827849-A | 6 [2 hydroxyl 3 (alkylamino radical) propoxyl group] benzofuran compounds and its application | 沈阳药科大学 | 2018-03-23 | — | — | CN | disclosed |