Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ANO1 | Q5XXA6 | 6/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28209630 | 0.94 | CASP3 (0.61) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL8550306 | 0.91 | MAOB (0.62) | CASP3SENP8SENP7SENP6KDM4E | |
| SCHEMBL28208757 | 0.85 | MAOB (0.66) | CASP3SENP8SENP7SENP6KDM4E | |
| SCHEMBL720239 | 0.85 | CASP3 (0.70) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL717397 | 0.83 | CASP3 (0.61) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL717067 | 0.82 | KDM4E (0.62) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL720265 | 0.82 | CASP3 (0.60) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL8545664 | 0.81 | KDM4E (0.53) | CASP3SENP8SENP7SENP6KDM4E | |
| SCHEMBL28217002 | 0.79 | NPC1 (0.50) | L3MBTL1KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL716903 | 0.78 | RAB9A (0.74) | L3MBTL1KDM4ENPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107935972-B | 5- [ 2-hydroxy-3- (isopropylamino) propoxy ] benzofuran derivative and application thereof | 沈阳药科大学 | 2020-06-02 | — | — | CN | claimed |
| CN-107935972-A | 5 [2 hydroxyl 3 (isopropylamine base) propoxyl group] benzofuran derivatives and its application | 沈阳药科大学 | 2018-04-20 | — | — | CN | claimed |
| CN-107935972-B | 5- [ 2-hydroxy-3- (isopropylamino) propoxy ] benzofuran derivative and application thereof | 沈阳药科大学 | 2020-06-02 | — | — | CN | disclosed |
| CN-107935972-A | 5 [2 hydroxyl 3 (isopropylamine base) propoxyl group] benzofuran derivatives and its application | 沈阳药科大学 | 2018-04-20 | — | — | CN | disclosed |