SCHEMBL2820893

SCHEMBL2820893

C=CCN(CC(=C)C)CC(=C)C

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.46
ALDH1A1 P00352 2/20 0.34
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2820192 0.95 CYP1A2 (0.46) CYP1A2ALDH1A1TP53TSHRHSD17B10
SCHEMBL10581837 0.90 CYP1A2 (0.43) CYP1A2ALDH1A1
SCHEMBL24127646 0.88 CYP1A2 (0.41) CYP1A2ALDH1A1
SCHEMBL24518459 0.88 CYP1A2 (0.41) CYP1A2ALDH1A1
SCHEMBL22112590 0.81 CYP1A2 (0.41) CYP1A2
SCHEMBL24636173 0.77 ALDH1A1 (0.38) CYP1A2ALDH1A1TP53TSHR
SCHEMBL13757277 0.77
SCHEMBL215590 0.76 CYP1A2 (0.60) CYP1A2HSD17B10TDP1
SCHEMBL10368806 0.76 KDM4E (0.32) ALDH1A1
SCHEMBL1137754 0.75 ALDH1A1 (0.37) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2592097-A1 Polymeric thickener composition S.P.C.M. SA (FR) 2013-05-15 EP claimed
US-20100247473-A1 POLYMERIC THICKENER COMPOSITION S.P.C.M. S.A. (FR) 2010-09-30 US claimed
EP-2222739-A2 POLYMERIC THICKENER COMPOSITION S.P.C.M. SA (FR) 2010-09-01 EP claimed
WO-2008107034-A2 POLYMERIC THICKENER COMPOSITION SNF SAS (FR) 2008-09-12 WO claimed
US-11590073-B2 Methods and compositions for reducing the feeling of vaginal dryness THE PROCTER & GAMBLE COMPANY (US) 2023-02-28 US disclosed
US-20210378952-A1 Methods And Compositions For Reducing The Feeling Of Vaginal Dryness PROCTER & GAMBLE (US) 2021-12-09 US disclosed
EP-3743046-A1 METHODS AND COMPOSITIONS FOR REDUCING THE FEELING OF VAGINAL DRYNESS The Procter & Gamble Company (US) 2020-12-02 EP disclosed
EP-3743044-A1 METHODS AND COMPOSITIONS FOR REDUCING THE FEELING OF VAGINAL DRYNESS The Procter & Gamble Company (US) 2020-12-02 EP disclosed
EP-3743047-A1 METHODS AND COMPOSITIONS FOR REDUCING THE FEELING OF VAGINAL DRYNESS The Procter & Gamble Company (US) 2020-12-02 EP disclosed
US-20200297622-A1 Methods And Compositions For Reducing The Feeling Of Vaginal Dryness THE PROCTER & GAMBLE COMPANY 2020-09-24 US disclosed
US-20200297630-A1 Methods And Compositions For Reducing The Feeling Of Vaginal Dryness THE PROCTER & GAMBLE COMPANY 2020-09-24 US disclosed
CN-111655233-A Methods and compositions for reducing vaginal dryness sensation 宝洁公司 2020-09-11 CN disclosed
WO-2019147876-A1 METHODS AND COMPOSITIONS FOR REDUCING THE FEELING OF VAGINAL DRYNESS THE PROCTER & GAMBLE COMPANY (US) 2019-08-01 WO disclosed
US-8936797-B2 Polymeric thickener composition S.P.C.M. S.A. (FR) 2015-01-20 US disclosed
EP-2592097-A1 Polymeric thickener composition S.P.C.M. SA (FR) 2013-05-15 EP disclosed
US-20100247473-A1 POLYMERIC THICKENER COMPOSITION S.P.C.M. S.A. (FR) 2010-09-30 US disclosed
EP-2222739-A2 POLYMERIC THICKENER COMPOSITION S.P.C.M. SA (FR) 2010-09-01 EP disclosed
WO-2008107034-A2 POLYMERIC THICKENER COMPOSITION SNF SAS (FR) 2008-09-12 WO disclosed
US-7306884-B2 Dye-containing curable composition, color filter prepared using the same, and process of preparing color filter FUJIFILM CORPORATION (JP) 2007-12-11 US disclosed
US-7306884-B2 Dye-containing curable composition, color filter prepared using the same, and process of preparing color filter FUJIFILM CORPORATION (JP) 2007-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200297622-A1 Methods And Compositions For Reducing The Feeling Of Vaginal Dryness MUC1, AVPR2, AVPR1A CYP1A2 2310/4885ALDH1A1 376/4885TP53 1529/4885
US-20210378952-A1 Methods And Compositions For Reducing The Feeling Of Vaginal Dryness NISCH, PGR, VIL1 CYP1A2 1941/4885ALDH1A1 4305/4885TP53 2048/4885
US-20200297630-A1 Methods And Compositions For Reducing The Feeling Of Vaginal Dryness SMURF1, VIL1, MUC1 CYP1A2 2607/4885ALDH1A1 1186/4885TP53 750/4885
US-11590073-B2 Methods and compositions for reducing the feeling of vaginal dryness NISCH, PGR, VIL1 CYP1A2 1941/4885ALDH1A1 4305/4885TP53 2048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.