SCHEMBL282092

SCHEMBL282092

COc1cc(O)ccc1N

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
CYP3A4 P08684 4/20 0.61
TDP1 Q9NUW8 2/20 0.61
MAOB P27338 1/20 0.61
TSHR P16473 1/20 0.61
HSD17B10 Q99714 1/20 0.61
HTT P42858 1/20 0.50
APP P05067 3/20 0.48
MAPT P10636 1/20 0.48
ADRA2B P18089 1/20 0.48
PTGS1 P23219 1/20 0.48
CHEK1 O14757 1/20 0.48
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
POLB P06746 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CTSL P07711 1/20 0.44
CTSB P07858 1/20 0.44
CHRNB4 P30926 1/20 0.44
CHRNA3 P32297 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30380626 1.00 ALDH1A1 (0.61) ALDH1A1CYP3A4TDP1MAOBTSHR
Hydrochloric Acid SCHEMBL29394681 0.98 ALDH1A1 (0.61) ALDH1A1CYP3A4TDP1MAOBTSHR
4-Aminophenol SCHEMBL17510191 0.92 MAOB (0.59) ALDH1A1CYP3A4TDP1MAOBTSHR
SCHEMBL926801 0.82 ALDH1A1 (0.59) ALDH1A1CYP3A4TDP1MAOBTSHR
SCHEMBL9310182 0.82 CA2 (0.58) ALDH1A1CYP3A4TDP1MAOBTSHR
SCHEMBL17498442 0.81 CA14 (0.44) ALDH1A1CYP3A4TDP1MAOBTSHR
SCHEMBL12474471 0.81 LTA4H (0.57) ALDH1A1CYP3A4TDP1MAOBTSHR
SCHEMBL12474539 0.80 ALDH1A1 (0.51) ALDH1A1CYP3A4TDP1MAOBTSHR
SCHEMBL12474487 0.80 TUBB4A (0.55) ALDH1A1CYP3A4TDP1MAOBTSHR
SCHEMBL16542005 0.80 ALDH1A1 (0.47) ALDH1A1CYP3A4TDP1MAOBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 412 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111769278-B Water system rechargeable zinc ion battery based on aromatic organic matter positive electrode material and application thereof 北京理工大学 2022-02-01 CN claimed
CN-111769278-A Water system rechargeable zinc ion battery based on aromatic organic matter positive electrode material and application thereof 北京理工大学 2020-10-13 CN claimed
EP-0459900-B2 Process for dyeing of keratinic fibres with 2,4-diamino-1,3-dimethoxybenzene in an acid medium and composition using this process OREAL (FR) 2002-08-28 EP claimed
CN-1060036-C Composition forthe oxidation dyeingof keratinous fiberes comprising a para-phenylenediamine containinga primary, secondary or tertiary amine function, a meta-phenylenediamine and a para-aminopheno.... OREAL (FR) 2001-01-03 CN claimed
US-6024769-A HAIR COLORS AND HAIR DYEING; RESISTANCE TO LIGHT, WASHINGS, PERSPIRATION AND ADVERSE WEATHER L'OREAL (FR) 2000-02-15 US claimed
US-5938792-A APPLYING TO KERATINOUS FIBERS UNDER BASIC CONDITIONS COMPOSITION COMPRISING AMINOINDOLE COUPLER, OXIDATION DYE PRECURSOR, OXIDIZING AGENT L'OREAL (FR) 1999-08-17 US claimed
EP-0663814-B1 PROCESS FOR DYEING KERATIN FIBRES USING AN ACID PH ALCOXYMETEPHENYLENEDIAMINE AND COMPOSITIONS THEREFOR OREAL (FR) 1999-04-28 EP claimed
US-5752982-A DYEING HAIR IN LIGHTFAST, WASHFAST COLORS L'OREAL (FR) 1998-05-19 US claimed
US-5683474-A HAIR DYES AND OXIDATION DYE PRECURSOR WITH OXIDIZERS L'OREAL (FR) 1997-11-04 US claimed
EP-0589952-B1 USE OF SUPLHUR METAAMINOPHENOLS FOR DYEING KERATINIC FIBRES, TINCTORIAL COMPOSITIONS AND NOVEL COMPOUNDS OREAL (FR) 1997-08-27 EP claimed
US-4960432-A Meta-phenylenediamines, process for preparation thereof, intermediate compounds and use of these meta-phenylenediamines as couplers for the oxidation dyeing of keratinous fibres and especially human hair L'OREAL (FR) 1990-10-02 US claimed
EP-0370880-A1 Trialkoxy-substituted m-phenylene diamines, process for their preparation, and their use as coupling agents in the oxidation dyeing of keratinic fibres, especially human hair L'OREAL (FR) 1990-05-30 EP claimed
US-4891045-A DYEING HAIR L'OREAL (FR) 1990-01-02 US claimed
US-4865619-A Use, as a coupler, of 2,4-diamino-1,3-dimethoxybenzene or one of its salts, in combination with oxidation dye precursors, for dyeing human hair, hair dyeing composition containing the said coupler and process for preparing the said coupler L'OREAL (FR) 1989-09-12 US claimed
US-4865617-A Dyeing compositions for keratinous fibres, especially for human hair, containing oxidation dye precursors and heterocyclic couplers L'OREAL (FR) 1989-09-12 US claimed
US-4865618-A New chloro-meta-phenylenediamines, their use as couplers in the oxidation dyeing of keratinous fibres, dyeing compositions for hair containing these compounds and dyeing process using the said L'OREAL (FR) 1989-09-12 US claimed
EP-0295474-A1 Chlorometaphenylenediamines, their use as coupling agents in oxydation colouring of keratinic fibres, colourity compositions for hair containing these compounds and colouring process using these compositions L'OREAL (FR) 1988-12-21 EP claimed
EP-0294669-A1 Metaphenylendiamines, process for their preparation, intermediate compounds and use of these metaphenylendiamines as couplers in oxydative colouring of keratinic fibres especially of human hair L'OREAL (FR) 1988-12-14 EP claimed
US-3981678-A HAIR DYES L'OREAL (FR) 1976-09-21 US claimed
US-3960476-A OXIDATION BASE GHILARDI GIULIANA 1976-06-01 US claimed