Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.39 |
| ▸ | ITK | Q08881 | 4/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 3/20 | 0.37 |
| ▸ | TGM2 | P21980 | 3/20 | 0.37 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.36 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
| ▸ | F13A1 | P00488 | 1/20 | 0.35 |
| ▸ | TGM1 | P22735 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28564782 | 0.72 | TGM2 (0.52) | EGFRITKPTPN1PTPN11BTK | |
| SCHEMBL4452979 | 0.71 | TGM2 (0.46) | EGFRPTPN1PTPN11TGM2GSTO1 | |
| SCHEMBL6524322 | 0.71 | CCNA2 (0.57) | EGFRITKPTPN1PTPN11TGM2 | |
| SCHEMBL28209516 | 0.70 | PTPN1 (0.41) | EGFRITKPTPN1PTPN11BTK | |
| Sulfuric Acid SCHEMBL5244029 | 0.70 | MAPK3 (0.41) | EGFRITKPTPN1PTPN11TGM2 | |
| SCHEMBL28810103 | 0.69 | CDK2 (0.48) | EGFRITKBTKMAPK3 | |
| SCHEMBL7641546 | 0.69 | TGM2 (0.50) | EGFRITKPTPN1PTPN11TGM2 | |
| SCHEMBL2828674 | 0.68 | EGFR (0.51) | EGFRITKPTPN1PTPN11BTK | |
| SCHEMBL21712524 | 0.68 | TGM2 (0.46) | EGFRITKBTKTGM2F13A1 | |
| SCHEMBL5931306 | 0.67 | TGM2 (0.44) | EGFRPTPN1PTPN11TGM2GSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107854720-A | Medicine-carried polyhydroxylated polymer embolism microball with radiography function and preparation method thereof | 苏州恒瑞迦俐生生物医药科技有限公司 | 2018-03-30 | — | — | CN | claimed |
| CN-107854720-A | Medicine-carried polyhydroxylated polymer embolism microball with radiography function and preparation method thereof | 苏州恒瑞迦俐生生物医药科技有限公司 | 2018-03-30 | — | — | CN | disclosed |